Results 111 to 120 of about 12,981,558 (250)

Effects of violet light exposure on aging dogs: a pilot study

Frontiers in Veterinary Science
Aging in dogs is known to induce various physical and brain alterations similar to dementia in humans. Concurrently with the recent extension of canine life expectancy, these age-related changes have imposed growing burdens on both dogs and their owners,
Kana Miyamoto, Nanami Ono, Shinichiro Kondo, Yukihiro Miwa, Yukihiro Miwa, Yukihiro Miwa, Kazuo Tsubota, Kazuo Tsubota, Makiko Ozawa, Takefumi Kikusui   +9 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Advancing Human-Animal Interaction to Counter Social Isolation and Loneliness in the Time of COVID-19: A Model for an Interdisciplinary Public Health Consortium. [PDF]

Animals (Basel), 2021
Hughes AM, Braun L, Putnam A, Martinez D, Fine A.   +4 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The Dog and Pony Show: A Critique of Human Animal Interaction Research [PDF]

, 2015
The scientific evidence supporting certain foundational anthrozooligical assertions regarding the human-animal bond is inadequate to support the definitional human to nonhuman-animal bond phenomenon defined as—a unique, bilateral benefit derived from ...
Willcockson, Sarah
core  

Introduction to Human-Animal Interaction: Insights from Social and Life Sciences

, 2023
Introduction to Human-Animal Interaction focuses on the human dimension of interacting with other animals. This book introduces recent developments, theories, and debates in the relatively new research area of Human-Animal Interaction (HAI) and focuses ...
Unknown Author (12488544)
core  

Navigating the nuances of studying animal facial behaviors with Facial Action Coding Systems

Frontiers in Ethology
Facial Action Coding Systems (FACS) are some of the most systematic and standardized methods for studying the physical aspects of animal facial behavior. Although FACS manuals provide some guidance on how to implement their coding system, they often lack
Brittany N. Florkiewicz, Brittany N. Florkiewicz   +1 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Reframing HRI Education : A Dialogic Reformulation of HRI Education to Promote Diverse Thinking and Scientific Progress

, 2017
Over the last few years, technological developments in semi-autonomous machines have raised awareness about the strategic importance of human-robot interaction (HRI) and its technical and social implications.
Giulia Messina Dahlberg, Lindblom, Jessica,, Billing, Erik A.,, Montebelli, Alberto, Billing, Erik,, Alberto Montebelli, Montebelli, Alberto,, Messina Dahlberg, Giulia,, Erik Billing, Lindblom, Jessica, Messina Dahlberg, Giulia, Billing, Erik, Billing, Erik A., Jessica Lindblom, Gothenburg University., Göteborgs universitet.   +15 more
core   +1 more source

Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia

Scientific Reports
Arboviral diseases transmitted by mosquitoes, including dengue, Chikungunya, Zika, yellow fever, West Nile virus (WNV), and Rift Valley fever (RVF), pose a significant public health challenge globally, particularly impacting populations in low and middle-
Samson Leta, Meskerem Mulisa Misgana, Bethel Befekadu Jaleta, Tesfaye Rufael Chibssa, Rob Lavigne, Jan Paeshuyse   +5 more
doaj   +1 more source