Results 61 to 70 of about 270,658 (298)
Frontiers in Bioengineering and Biotechnology, 2020 Microengineered systems provide an in vitro strategy to explore the variability of individual patient response to tissue engineering products, since they prefer the use of primary cell sources representing the phenotype variability.
Gabriele Nasello +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee +9 more
wiley +1 more source
Mimicking the kidney: A key role in organ-on-chip development [PDF]
, 2017 Pharmaceutical drug screening and research into diseases call for significant improvement in the effectiveness of current in vitro models. Better models would reduce the likelihood of costly failures at later drug development stages, while limiting or ...
Paoli, Roberto, Samitier i Martí, Josep
core +1 more source
3D printing techniques and their applications to organ-on-a-chip platforms: a systematic review [PDF]
, 2021 Three-dimensional (3D) in vitro models, such as organ-on-a-chip platforms, are an emerging and effective technology that allows the replication of the function of tissues and organs, bridging the gap amid the conventional models based on planar cell ...
Carvalho, Violeta Meneses +9 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
HIV Biosensors - The Potential of the Electrochemical Way
International Journal of Electrochemical Science, 2014 Because of high costs and time consuming common HIV tests, new ways in diagnosis, offering rapid, cheap, and accuracy possibility are looking for. One of the most promising fields is electrochemistry, providing very good specifity, relatively low price ...
Miguel Angel Merlos Rodrigo +6 more
doaj +1 more source
Where are we at regarding species translation? A review of the sbv IMPROVER challenge [PDF]
, 2017 Contact: Julia.Hoeng@pmi ...
Hoeng, J. +3 more
core
A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine [PDF]
, 2019 A high throughput histology (microTMA) platform was applied for testing drugs against tumors in a novel 3D heterotypic glioblastoma brain sphere (gBS) model consisting of glioblastoma tumor cells, iPSC-derived neurons, glial cells and astrocytes grown in
Ball, Graeme +7 more
core +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Vigilância Sanitária em Debate: Sociedade, Ciência & TecnologiaIntrodução: Os métodos tradicionais dos estudos pré-clínicos com animais podem não refletir com precisão a eficácia e a segurança de um composto em seres humanos.
Núbia Regina de Oliveira +2 more
doaj +1 more source