Results 91 to 100 of about 1,039,871 (304)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

An Abstraction Layer Exploiting Voice Assistant Technologies for Effective Human—Robot Interaction

Applied Sciences, 2021
A lot of people have neuromuscular problems that affect their lives leading them to lose an important degree of autonomy in their daily activities.
Ruben Alonso, Emanuele Concas, Diego Reforgiato Recupero   +2 more
doaj   +1 more source

Expressiveness in Human-Robot Interaction [PDF]

Interaction Design and Architecture(s), 2009
This article presents the design of Iromec, a modular robot companion tailored towards engaging in social exchanges with children with different disabilities with the aim to empower them to discover a wide rage of play styles from solitary to social and cooperative play. In particular this paper focuses on expressiveness as a fundamental feature of the
Marti, Patrizia, Giusti, Leonardo, Pollini, Alessandro, Rullo, Alessia   +3 more
openaire   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Producing unexpected emotional expressions in others reduces one’s own agency

Scientific Reports
The sense of agency (SoA), or the subjective feeling of causing and controlling action outcomes, is fundamental to how we engage with the world. In the present study, we investigated how SoA is influenced when individuals unintentionally elicit emotional
Ilkay Ari, Davide De Tommaso, Agnieszka Wykowska   +2 more
doaj   +1 more source

Child-Centric Robot Dialogue Systems: Fine-Tuning Large Language Models for Better Utterance Understanding and Interaction

Sensors
Dialogue systems must understand children’s utterance intentions by considering their unique linguistic characteristics, such as syntactic incompleteness, pronunciation inaccuracies, and creative expressions, to enable natural conversational engagement ...
Da-Young Kim, Hyo Jeong Lym, Hanna Lee, Ye Jun Lee, Juhyun Kim, Min-Gyu Kim, Yunju Baek   +6 more
doaj   +1 more source

A Primer for Conducting Experiments in Human–Robot Interaction

ACM Trans. Hum. Robot Interact., 2020
We provide guidelines for planning, executing, analyzing, and reporting hypothesis-driven experiments in Human–Robot Interaction (HRI). The intended audience are researchers in the field of HRI who are not trained in empirical research but who are ...
Guy Hoffman, Xuan Zhao
semanticscholar   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source

Understanding action concepts from videos and brain activity through subjects’ consensus

Scientific Reports, 2022
In this paper, we investigate brain activity associated with complex visual tasks, showing that electroencephalography (EEG) data can help computer vision in reliably recognizing actions from video footage that is used to stimulate human observers ...
Jacopo Cavazza, Waqar Ahmed, Riccardo Volpi, Pietro Morerio, Francesco Bossi, Cesco Willemse, Agnieszka Wykowska, Vittorio Murino   +7 more
doaj   +1 more source