Results 101 to 110 of about 2,199,898 (317)

RESEARCH ON HEAVY METAL POLLUTION OF THE RIVER MUREŞ IN HUNEDOARA COUNTY DUE TRIBUTARIES AFFECTED BY HUMAN ACTIVITIES, INDUSTRIAL AND MINING [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
Mureş crosses over a length of 105 km, a broad tectonic corridor between mountains Şureanu, Poiana Rusca Mountains and the Apuseni Mountains in the north.
SZOLLOSI-MOŢA ANDREI , SÂRBU ROMULUS
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Experiencing VOS: A Visual Orientation System

open access: yes, 2018
This demo introduces VOS - a Visual Orientation System. Since orientation without visual cues is challenging for humans, situations in which visibility is limited pose hindrance and sometimes a threat to human activities.
Woźniak, Paweł W.   +4 more
core   +1 more source

Does human disturbance affect physiological traits of Two-banded Plovers nesting on an urban beach?

open access: yesAvian Conservation and Ecology, 2023
In coastal Patagonia, Argentina, shorebird breeding habitats overlap with high levels of human recreational activities, such as dog-walking and driving motorized vehicles.
Glenda D. Hevia   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Identifying Time-Consuming Human Modelling Tool Activities [Elektronisk resurs]

open access: yes, 2006
The aim of this study was to identify and measure time-consuming human modelling tool activities. Five human modelling tool users at Volvo were observed for five days each. The results showed a wide distribution of both indirect and direct working tasks,
Nielsen, Emma   +5 more
core  

Attribution Identification of Runoff Change Before and After Impoundment in the Three Gorges Reservoir Area Based on Budyko Hypothesis

open access: yesShuitu Baochi Xuebao
[Objective] Runoff changes under the combined influence of climate change and human activities. Exploring the temporal and spatial evolution of runoff and its causes has important guiding significance for the scientific operation of reservoirs and the ...
CHEN Meng’en   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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