Results 91 to 100 of about 13,117,722 (295)

Does human disturbance affect physiological traits of Two-banded Plovers nesting on an urban beach?

open access: yesAvian Conservation and Ecology, 2023
In coastal Patagonia, Argentina, shorebird breeding habitats overlap with high levels of human recreational activities, such as dog-walking and driving motorized vehicles.
Glenda D. Hevia   +3 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing the impact of human activities in a NW Iberian Roman mining landscape for the last 2500 years [PDF]

open access: yes, 2014
This article was made available through the Brunel Open Access Publishing Fund.Little is known about the impact of human activities during Roman times on NW Iberian mining landscapes beyond the geomorphological transformations brought about by the use of
López-Merino, L   +15 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Attribution Identification of Runoff Change Before and After Impoundment in the Three Gorges Reservoir Area Based on Budyko Hypothesis

open access: yesShuitu Baochi Xuebao
[Objective] Runoff changes under the combined influence of climate change and human activities. Exploring the temporal and spatial evolution of runoff and its causes has important guiding significance for the scientific operation of reservoirs and the ...
CHEN Meng’en   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Fire management in mount Kenya:

open access: yesBiodiversidade Brasileira, 2019
This paper proposes an Integrated Fire Management (IFM) framework that can be used to support communities and resource managers in finding effective and efficient approaches to prevent damaging fires, as well as to maintain desirable fire regimes in ...
Kevin Wafula Nyongesa
doaj   +1 more source

Renin Activity in Human Uterus

open access: yesExperimental Biology and Medicine, 1970
SummaryRenin activity was determined in uterine samples obtained from nonpregnant women undergoing hysterectomy and from pregnant women during cesarean section. All samples were full-thickness biopsy specimens from the lower uterine segment. In women having normal menstrual cycles, there was no significant difference between the mean renin activities ...
G W, Geelhoed, A J, Vander, J, Carlson
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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