Results 81 to 90 of about 6,271,732 (295)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Post-Activation Potentiation Enhancement of Countermovement Jump Performance using Velocity-based Conditioning Protocols with High-loads in Active Men and Women

Motricidade
Post-activation performance enhancement (PAPE) refers to the temporary improvement in physical abilities resulting from a previous conditioning activity (CA), and velocity-based resistance training has been proposed to optimise PAPE.
Rafael Peixoto, Rui Canário-Lemos, Tiago Moreira, Guilherme Vilela, Gabriela Lucas Chaves, Felipe José Aidar, Filipe Casanova, Gabriela Monteiro, Victor Reis, José Vilaça-Alves   +9 more
doaj   +1 more source

Human activity in the web

Physical Review E, 2009
10 pages, 9 figures.
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dynamics of sulfate and nitrate in a temperate stream network: combining multi-isotope analysis and generalized linear mixed-effects models for precautionary conservation

Progress in Earth and Planetary Science
Environmental pollution in stream networks is a major concern. In this study, the effects of land-use and geological characteristics on basin-scale sulfate and nitrate dynamics in the Chikusa River basin, Hyogo, Japan, where substantial environmental ...
Lei Fujiyoshi, Ichiro Tayasu, Shiho Yabusaki, Takashi F. Haraguchi, Chikage Yoshimizu, Ken’ichi Ohkushi, Fumiko Furukawa, Masayuki Itoh, Tadashi Yokoyama, Hiromune Mitsuhashi   +9 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

RESEARCH ON HEAVY METAL POLLUTION OF THE RIVER MUREŞ IN HUNEDOARA COUNTY DUE TRIBUTARIES AFFECTED BY HUMAN ACTIVITIES, INDUSTRIAL AND MINING [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
Mureş crosses over a length of 105 km, a broad tectonic corridor between mountains Şureanu, Poiana Rusca Mountains and the Apuseni Mountains in the north.
SZOLLOSI-MOŢA ANDREI , SÂRBU ROMULUS
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source