Results 31 to 40 of about 111,766 (263)
β-Cell Regeneration Mediated by Human Bone Marrow Mesenchymal Stem Cells
PLoS ONE, 2012 Bone marrow mesenchymal stem cells (BMSCs) have been shown to ameliorate diabetes in animal models. The mechanism, however, remains largely unknown. An unanswered question is whether BMSCs are able to differentiate into β-cells in vivo, or whether BMSCs are able to mediate recovery and/or regeneration of endogenous β-cells.
Anna Milanesi +7 more
openaire +4 more sources
Neural Regeneration ResearchOur previous study demonstrated that combined transplantation of bone marrow mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal degeneration that are superior to transplantation of retinal progenitor cells ...
Chunge Ren +12 more
doaj +1 more source
Haematologica, 2008 Background Human mesenchymal stem cells are potential agents for tissue regeneration, enhancing hematopoietic stem cell transplantation and delivering genes of therapeutic interest.
Charalampia Kyriakou +4 more
doaj +1 more source
Bioreactor Expansion of Human Adult Bone Marrow‐Derived Mesenchymal Stem Cells [PDF]
STEM CELLS, 2006 Supplementation of mesenchymal stem cells (MSCs) during hematopoietic stem cell (HSC) transplantation alleviates complications such as graft-versus-host disease, leading to a speedy recovery of hematopoiesis. To meet this clinical demand, a fast MSC expansion method is required.
Chen, X. +4 more
openaire +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Isolation and characterization of mesenchymal stem cells obtained from reusable and disposable bone marrow collection filters [PDF]
Einstein (São Paulo), 2012 Objective: To compare human mesenchymal stem cells obtainedfrom reusable and disposable filters and to characterize themaccording to the criteria of the International Society of CellularTherapy.
Glaziane Cordeiro de Deus +6 more
doaj
Stem Cell Therapy in Stargardt Disease: A Systematic Review
Journal of Ophthalmic & Vision Research, 2023 This article aimed to review current literature on the safety and efficacy of stem cell therapy in Stargardt disease. A comprehensive literature search was performed, and two animal and eleven human clinical trials were retrieved.
Atousa Moghadam Fard +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Journal of Tissue Engineering, 2014 The development of biomaterial surfaces possessing the topographical cues that can promote mesenchymal stem cell recruitment and, in particular, those capable of subsequently directing osteogenic differentiation is of increasing importance for the ...
Mura M McCafferty +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source