Results 31 to 40 of about 180,484 (312)

Human stem cells transplanted into the rat stroke brain migrate to the spleen via lymphatic and inflammation pathways

Haematologica, 2019
Despite mounting evidence of a massive peripheral inflammatory response accompanying stroke, the ability of intracerebrally transplanted cells to migrate to the periphery and sequester systemic inflammation remains unexamined.
Kaya Xu, Jea-Young Lee, Yuji Kaneko, Julian P. Tuazon, Fernando Vale, Harry van Loveren, Cesario V. Borlongan   +6 more
doaj   +1 more source

Identification of the Factor That Leads Human Mesenchymal Stem Cell Lines into Decellularized Bone

Bioengineering, 2022
Hematopoiesis is maintained by the interaction of hematopoietic stem cells (HSCs) and bone marrow mesenchymal stem cells (MSCs) in bone marrow microenvironments, called niches.
Anri Koyanagi, Iichiroh Onishi, Karin Muraoka, Ikue Sato, Shingo Sato, Tsuyoshi Kimura, Akio Kishida, Kouhei Yamamoto, Masanobu Kitagawa, Morito Kurata   +9 more
doaj   +1 more source

β-Cell Regeneration Mediated by Human Bone Marrow Mesenchymal Stem Cells

PLoS ONE, 2012
Bone marrow mesenchymal stem cells (BMSCs) have been shown to ameliorate diabetes in animal models. The mechanism, however, remains largely unknown. An unanswered question is whether BMSCs are able to differentiate into β-cells in vivo, or whether BMSCs are able to mediate recovery and/or regeneration of endogenous β-cells.
Anna Milanesi, Jang-Won Lee, Zhenhua Li, Stefano Da Sacco, Valentina Villani, Vanessa Cervantes, Laura Perin, John S Yu   +7 more
openaire   +4 more sources

Vitamin D metabolism in human bone marrow stromal (mesenchymal stem) cells [PDF]

Metabolism, 2013
There are many human extra-renal tissues and cells that biosynthesize 1α,25-dihydroxyvitamin D (1α,25(OH)(2)D) by the action of CYP27B1/1α-hydroxylase. Human marrow stromal cells (hMSCs), also known as mesenchymal stem cells, were isolated from marrow discarded from well-characterized, consented subjects during common orthopedic procedures.
Shuo, Geng, Shuanhu, Zhou, Zhenggang, Bi, Julie, Glowacki   +3 more
openaire   +2 more sources

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]

, 2019
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja, Beez, Christien, Blankenstein, Antje, Catar, Rusan, Duda, Georg, Geissler, Sven, Jacobi, Dorit, Jürchott, Karsten, Kamhieh-Milz, Julian, Krüger, David, Krüger, Ulrike, Moll, Guido, Qazi, Taimoor Hasan, Reinke, Petra, Reinke, Simon, Richter, Sarina, Sass, Frauke Andrea, Schlickeiser, Stephan, Schoon, Janosch, Souidi, Naima, Streitz, Mathias, Strunk, Dirk, Zemojtel, Tomasz   +22 more
core   +1 more source

Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature

Journal of Medical Case Reports, 2020
Background Premature ovarian failure is a relatively common condition that affects 1–3% of adult women. Premature ovarian failure occurs when there is loss of ovarian function in women younger than 40 years of age.
Prosper Igboeli, Abdeljabar El Andaloussi, Ujalla Sheikh, Hajra Takala, Amro ElSharoud, Ashley McHugh, Larisa Gavrilova-Jordan, Steven Levy, Ayman Al-Hendy   +8 more
doaj   +1 more source

Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]

, 2004
Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Aicher, A, Assmus, B, Dimmeler, S, Heeschen, C, Honold, J, Lehmann, R, Martin, H, Walter, DH, Zeiher, AM   +8 more
core   +1 more source

Optimization and Comparison of the PolyFect Gene Delivery Method in Three Different Kinds of Mesenchymal Stem Cell Types [PDF]

Cell Journal, 2010
Objective: The aim of this study was optimization of the PolyFect gene delivery methodof pcDNA3.1 expression vector transfected with the mouse pdx-1 gene in three differentkinds of mesenchymal stem cells and Hepa cells as well as comparison of ...
Pezhman Fard-Esfahani, Neda Memari, Mehdi Kadivar   +2 more
doaj  

miR-139-5p Was Identified as Biomarker of Different Molecular Subtypes of Breast Carcinoma

Frontiers in Oncology, 2022
Located on chromosome 11q13.4, miR-139-5p has been confirmed by several studies as a possible attractive biomarker for cancer, including breast cancer, but its mechanism of correlation in different molecular subtypes of breast cancer has not been ...
Haohang Sun, Ji Dai, Mengze Chen, Qi Chen, Qiong Xie, Weijun Zhang, Guoqing Li, Meidi Yan   +7 more
doaj   +1 more source

Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury. [PDF]

, 2016
FGF-10 can prevent or reduce lung specific inflammation due to traumatic or infectious lung injury. However, the exact mechanisms are poorly characterized.
Bai, Chunxue, Liu, Jie, Pan, Jue, Qu, Jieming, Rong, Linyi, Seeley, Eric J, Song, Yuanlin, Tang, Xinjun, Tong, Lin, Wang, Qin, Zhou, Jian, Zhu, Xiaodan   +11 more
core   +1 more source