Results 181 to 190 of about 165,036 (300)

Cooperation between myofibril growth and costamere maturation in human cardiomyocytes. [PDF]

Front Bioeng Biotechnol, 2022
Shi H, Wang C, Gao BZ, Henderson JH, Ma Z.   +4 more
europepmc   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Effect of Hypoxia on Irisin Secretion by Human Cardiomyocytes. [PDF]

In Vivo
Grzeszczuk M, Ciesielska U, Rusak A, Kulus MJ, Haczkiewicz-Leśniak K, Jabłońska K, Kmiecik A, Podhorska-Okołów M, Dzięgiel P, Nowińska K.   +9 more
europepmc   +1 more source

Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice. [PDF]

Nat Med, 2023
Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN.   +12 more
europepmc   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

GSK-3α regulates miRNAs associated with transcriptional and metabolic processes in human cardiomyocytes under hypoxia. [PDF]

Biochem J
Ahmad F, Marzook H, Idris M, Dawuod OI, Srinivas M, Karim A, Saleh MA, Qaisar R.   +7 more
europepmc   +1 more source

Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19. [PDF]

Cells, 2023
Huynh TV, Rethi L, Lee TW, Higa S, Kao YH, Chen YJ.   +5 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

SNTA1-deficient human cardiomyocytes show shorter field potential duration and slower conduction velocity. [PDF]

Sci Rep
Dong T, Zhao Y, Zhang M, Lang WY, Liu DY, Zhang KS, Wang YJ, Li L, Lian J, Yao HB, Zhang HY, Jin HF, Lu T, Shen L, Yue LL, Lin Y.   +15 more
europepmc   +1 more source