Results 141 to 150 of about 100,666 (169)
Effects of the nucleoside analog 2'-nor-2'-deoxyguanosine on human cytomegalovirus replication
Michael J. Tocci+4 more
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Humanes Cytomegalovirus (HCMV)
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Pharmacology & Therapeutics, 2003
Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause of birth defects, as well as an important pathogen for immunocompromised individuals. The viral nucleocapsid containing a linear double-stranded DNA of 230 kb is surrounded by a proteinaceous tegument, which is itself enclosed by a loosely applied lipid bilayer ...
LANDOLFO, Santo Giuseppe+3 more
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Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause of birth defects, as well as an important pathogen for immunocompromised individuals. The viral nucleocapsid containing a linear double-stranded DNA of 230 kb is surrounded by a proteinaceous tegument, which is itself enclosed by a loosely applied lipid bilayer ...
LANDOLFO, Santo Giuseppe+3 more
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The pathogenesis of human cytomegalovirus
The Journal of Pathology, 2014AbstractHuman cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft recipient and AIDS patients. More recently, it has been recognized as a pathogen for those admitted to intensive care units, for the elderly and for the general population.
Matthew B. Reeves+2 more
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New England Journal of Medicine, 1972
KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
Kathleen Hayes+3 more
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KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
Kathleen Hayes+3 more
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Cytomegalovirus and human immunosenescence
Reviews in Medical Virology, 2008Abstract‘Immunosenescence’ is an imprecise term used to describe deleterious age‐associated changes to immune parameters observed in all mammals studied so far. Primarily anecdotal evidence implies that failing immunity is responsible for the increased incidence and severity of infectious disease in old people.
Anders Wikby+4 more
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2008
Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
Thomas Shenk, Eain Murphy
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Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
Thomas Shenk, Eain Murphy
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Human cytomegalovirus infection and atherothrombosis
Journal of Thrombosis and Thrombolysis, 2011Vascular endothelium, as a key regulator of hemostasis, mediates vascular dilatation, prevents platelet adhesion, and inhibits thrombin generation. Endothelial dysfunction caused by acute or chronic inflammation, such as in atherosclerosis, creates a proinflammatory environment which supports leukocyte transmigration toward inflammatory sites, and at ...
Popović, Milan+5 more
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Human Cytomegalovirus microRNAs
2008MicroRNAs (miRNAs) are approximately 22 nucleotide RNAs that mediate the posttranscriptional regulation of gene expression. miRNAs regulate diverse cellular processes such as development, differentiation, cell cycling, apoptosis, and immune responses.
E. Yang+3 more
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