Results 11 to 20 of about 8,732,052 (351)

Human Cytomegalovirus and Autoimmune Diseases: Where Are We?

Viruses, 2021
Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes latency in poorly differentiated myeloid precursors from where it can ...
F. Gugliesi, Selina Pasquero, G. Griffante, S. Scutera, Camilla Albano, Sergio Fernando Castillo Pacheco, G. Riva, Valentina Dell’Oste, Matteo Biolatti   +8 more
semanticscholar   +1 more source

Control of human cytomegalovirus replication by liver resident natural killer cells

Nature Communications, 2023
Natural killer cells play important roles in the immune response to human cytomegalovirus infection. Here the authors implicate donor-derived liver resident natural killer cells in the control of human cytomegalovirus infection by analysis of perfusates ...
Calum Forrest, Thomas J. G. Chase, Antonia O. Cuff, Dionas Maroulis, Reza Motallebzadeh, Amir Gander, Brian Davidson, Paul Griffiths, Victoria Male, Matthew Reeves   +9 more
doaj   +1 more source

Decoding Human Cytomegalovirus [PDF]

Science, 2012
Dissecting HCMV Gene Expression Most of us are infected with human cytomegalovirus (HCMV), but severe disease is almost always limited to immunocompromised individuals or newborn infants. The virus has a relatively large (∼240 kb) DNA genome and shows a complex pattern of gene transcription, hinting at a complex ...
Stern-Ginossar, N., Weisburd, B., Michalski, A., Vu Khanh Le, T., Hein, M., Huang, S., Ma, M., Shen, B., Qian, S., Hengel, H., Mann, M., Ingolia, N., Weissman, J.   +12 more
openaire   +3 more sources

Clinical Diagnostic Testing for Human Cytomegalovirus Infections.

Journal of Infectious Diseases, 2020
Human cytomegalovirus (HCMV) infections are among the most common complications arising in transplant patients, elevating the risk of various complications including loss of graft and death.
R. Razonable, N. Inoue, Swetha Pinninti, S. Boppana, T. Lazzarotto, L. Gabrielli, G. Simonazzi, P. Pellett, D. Schmid   +8 more
semanticscholar   +1 more source

Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection

Nature Communications, 2020
The co-evolution and co-existence of viral pathogens with their hosts for millions of years is reflected in dynamic virus-host protein-protein interactions (PPIs) that are intrinsic to the spread of infections.
Yutaka Hashimoto, Xinlei Sheng, Laura A Murray-Nerger, I. Cristea   +3 more
semanticscholar   +1 more source

The Status of Vaccine Development Against the Human Cytomegalovirus.

Journal of Infectious Diseases, 2020
Numerous candidate vaccines against cytomegalovirus (CMV) infection and disease are in development. Whereas the previous article [1] provides background and opinions about the issues relating to vaccination, this article provides specifics about the ...
S. Plotkin, Dai Wang, A. Oualim, D. Diamond, C. Kotton, S. Mossman, A. Carfi, D. Anderson, P. Dormitzer   +8 more
semanticscholar   +1 more source

A fully human neutralizing monoclonal antibody targeting a highly conserved epitope of the human cytomegalovirus glycoprotein B.

PLoS ONE, 2023
Human cytomegalovirus causes severe diseases in children (by congenital infection) and immunocompromised patients. Treatment with antiviral agents, such as ganciclovir, is limited by their toxicity.
Miwa Okamoto, Rika Kurino, Ryu Miura, Kenzo Takada   +3 more
doaj   +1 more source

Human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection

Haematologica, 2008
Background Human cytomegalovirus infection is the most frequent viral complication in patients undergoing hematopoietic stem cell transplantation.
Daniele Lilleri, Chiara Fornara, Antonella Chiesa, Daniela Caldera, Emilio Paolo Alessandrino, Giuseppe Gerna   +5 more
doaj   +1 more source

Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]

, 2006
BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice, Hai, Rong, Li, Hongjian, Liu, Fenyong, Rider, Paul, Umamoto, Sean   +5 more
core   +3 more sources

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]

, 1984
Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling, AB Rickinson, ARM Townsend, ARM Townsend, B Roizman, BT Rouse, C Taswell, deSt Fazekas, DR Mayo, G Berke, GM Keil, GV Quinnan, JB Hudson, JD Meyers, JD Shanley, JE Grundy, JK Chantler, JR Bennink, JR Marks, LK Borysiewicz, LR Gooding, M Ho, Matthias J. Reddehase, MC Jordan, MF Stinski, MJ Bevan, MJ Imperiale, MJ Reddehase, MJ Reddehase, MR Green, PG Spear, RJ Watson, RM Stenberg, RW Honess, SS Tevethia, UH Koszinowski, Ulrich H. Koszinowski   +36 more
core   +1 more source