Results 21 to 30 of about 8,385,867 (288)
Frontiers in Microbiology, 2019 Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT).
L. Stern +6 more
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Human Cytomegalovirus Glycoproteins
Intervirology, 1996 The complex biology of human cytomegalovirus (HCMV) necessarily begins with an initial interaction between the envelope of the infectious virion and the host cell. Understanding the initial events of infection will require a further analysis of the glycoprotein components of the virion envelope as well as their expression in the membranes of the ...
William J. Britt, Michael Mach
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Pathogen at the Gates: Human Cytomegalovirus Entry and Cell Tropism
Viruses, 2018 The past few years have brought substantial progress toward understanding how human cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that it infects.
Christopher C. Nguyen, J. Kamil
semanticscholar +1 more source
Functional single-cell genomics of human cytomegalovirus infection
Nature Biotechnology, 2019 Understanding how viral and host factors interact and how perturbations impact infection is the basis for designing antiviral interventions. Here we define the functional contribution of each viral and host factor involved in human cytomegalovirus ...
Marco Y. Hein, J. Weissman
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The Human Cytomegalovirus, from Oncomodulation to Oncogenesis
Viruses, 2018 Besides its well-described impact in immunosuppressed patients, the role of human cytomegalovirus (HCMV) in the pathogenesis of cancer has been more recently investigated.
G. Herbein
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Human Cytomegalovirus Cell Tropism and Host Cell Receptors
Vaccines, 2019 In the 1970s–1980s, a striking increase in the number of disseminated human cytomegalovirus (HCMV) infections occurred in immunosuppressed patient populations.
G. Gerna, A. Kabanova, D. Lilleri
semanticscholar +1 more source
The Oncogenicity of Human Cytomegalovirus [PDF]
, 2013 The potential role of Human cytomegalovirus (hCM) infection in promoting neoplasia is an active area of scientific research. [1] Although still controversial, there is a growing body of evidence that links hCMV infection to a variety of malignancies, including those of the breast, prostate, colon, lung and brain (gliomas).
David M. Aboulafia, Prakash Vishnu
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Lack of cytomegalovirus detection in human glioma [PDF]
Virology Journal, 2017 Gliomas are the most common brain tumors and include a variety of histologic types and grades of malignancy. They arise from glial cells and represent approximately 70% of the primary brain tumors. According to the criteria of the World Health Organization (WHO), the majority of gliomas can be classified into four grades of malignancy (I-IV).
Garcia-Martinez, Araceli +7 more
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Maternal Immunity and the Natural History of Congenital Human Cytomegalovirus Infection
Viruses, 2018 Congenital human cytomegalovirus (HCMV) is the most common viral infection of the developing fetus, and a significant cause of neurodevelopmental abnormalities in infants and children.
W. Britt
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Human cytomegalovirus persistence
Cellular Microbiology, 2012 Viral persistence is the rule following infection with all herpesviruses. The β-herpesvirus, human cytomegalovirus (HCMV), persists through chronic and latent states of infection. Both of these states of infection contribute to HCMV persistence and to the high HCMV seroprevalence worldwide.
Patricia Zagallo +2 more
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