Results 41 to 50 of about 8,732,052 (351)

Impact of sequence variation in the ul128 locus on production of human cytomegalovirus in fibroblast and epithelial cells [PDF]

open access: yes, 2013
The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A.
A. J. Davison   +87 more
core   +2 more sources

Subconfluent ARPE-19 Cells Display Mesenchymal Cell-State Characteristics and Behave like Fibroblasts, Rather Than Epithelial Cells, in Experimental HCMV Infection Studies

open access: yesViruses, 2023
Human cytomegalovirus (HCMV) has a broad cellular tropism and epithelial cells are important physiological targets during infection. The retinal pigment epithelial cell line ARPE-19 has been used to model HCMV infection in epithelial cells for decades ...
Preethi Golconda   +2 more
doaj   +1 more source

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

open access: yes, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang   +8 more
core   +1 more source

Belatacept associated - cytomegalovirus retinitis in a kidney transplant recipient: a case report and review of the literature

open access: yesBMC Ophthalmology, 2020
Background To report the first case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transplant recipient. Case presentation A 76-year-old African male renal allograft recipient was admitted for acute visual loss of the ...
Pierre-Guillaume Deliège   +5 more
doaj   +1 more source

Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation. [PDF]

open access: yesPLoS ONE, 2016
Congenital cytomegalovirus infections are a leading cause of neurodevelopmental disorders in human and represent a major health care and socio-economical burden. In contrast with this medical importance, the pathophysiological events remain poorly known.
Robin Cloarec   +18 more
doaj   +1 more source

Episodic vestibular symptoms in children with a congenital cytomegalovirus infection [PDF]

open access: yes, 2019
Objective: Congenital cytomegalovirus (cCMV) infection is the most common non-genetic cause of sensorineural hearing loss in children. Although cCMV-induced vestibular loss is demonstrated in several studies, the occurrence of vertigo has been described ...
Dhondt, Cleo   +3 more
core   +1 more source

Subversion of Immune Response by Human Cytomegalovirus

open access: yesFrontiers in Immunology, 2019
Human cytomegalovirus (HCMV) is the most common cause of congenital infections and is an important pathogen in immunocompromised individuals. Despite a robust host immune system, HCMV able to replicate, evade host defenses, establish latency for life.
A. Patro
semanticscholar   +1 more source

Cytomegalovirus infection in patients attending a tertiary care hospital – single center experience

open access: yesIranian Journal of Microbiology
Background and Objectives: Human cytomegalovirus infection poses an important public health issue. This issue in India has not received enough attention.
Bashir Ahmad Fomda   +7 more
doaj   +1 more source

Preservation of Anti-cytomegalovirus Activity in Human Milk Following High-Pressure Processing Compared to Holder Pasteurization

open access: yesFrontiers in Nutrition, 2022
Pasteurized donor human milk is recommended for hospitalized preterm infants when mother’s own milk is unavailable. Our aim was to compare the antiviral activity of human milk processed by Holder pasteurization (HoP) or high-pressure processing (HPP ...
Akash Kothari   +17 more
doaj   +1 more source

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex [PDF]

open access: yes, 2017
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health.
Adler, Stuart P.   +19 more
core   +3 more sources

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