Results 41 to 50 of about 100,666 (169)

MicroRNA-613 is downregulated in HCMV-positive glioblastoma and inhibits tumour progression by targeting arginase-2

open access: yesTumor Biology, 2017
Glioblastoma is the most common and malignant tumour that occurs primarily in nervous system and has a high morbidity. Research on glioblastoma has recently focused on human cytomegalovirus, belonging to the beta subfamily of Herpesviridae that plays ...
Yan Wang   +6 more
doaj   +1 more source

Antibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6)

open access: yesViruses, 2017
Porcine cytomegalovirus (PCMV) infection is widely prevalent among pigs, and PCMV is one of the viruses which may be transmitted during xenotransplantation using pig cells, tissues, or organs. While human cytomegalovirus (HCMV) is a major risk factor for
Uwe Fiebig   +6 more
doaj   +1 more source

Microbial populations under selection [PDF]

open access: yesin: Probabilistic Structures in Evolution (E. Baake, A. Wakolbinger, eds.), EMS Press, Berlin, 2021, pp. 43-68, 2020
This chapter gives a synopsis of recent approaches to model and analyse the evolution of microbial populations under selection. The first part reviews two population genetic models of Lenski's long-term evolution experiment with Escherichia coli, where models aim at explaining the observed curve of the evolution of the mean fitness.
arxiv  

High ocular CMV copies and mismatched receipts may predict poor visual prognosis in CMV retinitis patients following allogeneic haematopoietic stem cell transplantation

open access: yesBMC Ophthalmology, 2017
Background To summarize the clinical characteristics and potential factors affecting the visual outcomes in patients with cytomegalovirus retinitis following allogeneic haematopoietic stem cell transplantation (HSCT).
Yuehong Zhang   +6 more
doaj   +1 more source

Understanding HCMV Latency Using Unbiased Proteomic Analyses

open access: yesPathogens, 2020
Human cytomegalovirus (HCMV) establishes either a latent (non-productive) or lytic (productive) infection depending upon cell type, cytokine milieu and the differentiation status of the infected cell.
Emma Poole, John Sinclair
doaj   +1 more source

Pre-Transplant Platelet Refractoriness and Alternative Donors Are Associated With Cytomegalovirus Retinitis in Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundCytomegalovirus retinitis is a severe, vision-threatening opportunistic infection in an immunodeficient population. Reports on cytomegalovirus retinitis in hematopoietic stem cell transplant recipients due to severe aplastic anemia have been ...
Yuehong Zhang   +8 more
doaj   +1 more source

Lack of cytomegalovirus detection in human glioma [PDF]

open access: yesVirology Journal, 2017
Gliomas are the most common brain tumors and include a variety of histologic types and grades of malignancy. They arise from glial cells and represent approximately 70% of the primary brain tumors. According to the criteria of the World Health Organization (WHO), the majority of gliomas can be classified into four grades of malignancy (I-IV).
Garcia-Martinez, Araceli   +7 more
openaire   +7 more sources

Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH

open access: yesCommunications Biology, 2022
A panel of neutralizing human monoclonal antibodies targeting human cytomegalovirus offers a combination approach geared toward virus entry and replication to prevent viral dissemination.
Andrea J. Parsons   +6 more
doaj   +1 more source

Chromatin control of human cytomegalovirus infection

open access: yesmBio, 2023
Human cytomegalovirus (HCMV) is a betaherpesvirus that establishes lifelong infection in its host and can cause severe comorbidities in individuals with suppressed or compromised immune systems.
Stephen M. Matthews   +2 more
doaj   +1 more source

The dangers in algorithms learning humans' values and irrationalities [PDF]

open access: yesarXiv, 2022
For an artificial intelligence (AI) to be aligned with human values (or human preferences), it must first learn those values. AI systems that are trained on human behavior, risk miscategorising human irrationalities as human values -- and then optimising for these irrationalities.
arxiv  

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