Results 51 to 60 of about 12,768,039 (194)

Resveratrol delays senescence of human dental pulp stem cells via activating the SIRT1-mitochondrial autophagy

open access: yesScientific Reports
Human dental pulp stem cells (hDPSCs) senescence impairs their proliferation and osteogenic differentiation, critical for dental stem cell therapy. This study evaluated the effects of Resveratrol on the senescence of hDPSCs to explore new therapeutic ...
Zelu Li   +10 more
doaj   +1 more source

Use of a 3D Floating Sphere Culture System to Maintain the Neural Crest-Related Properties of Human Dental Pulp Stem Cells

open access: yesFrontiers in Physiology, 2018
Human dental pulp is considered an interesting source of adult stem cells, due to the low-invasive isolation procedures, high content of stem cells and its peculiar embryological origin from neural crest.
Alessandra Pisciotta   +8 more
doaj   +1 more source

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

open access: yesOral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang   +5 more
wiley   +1 more source

Cdc42 is essential for the polarized movement and adhesion of human dental pulp stem cells [PDF]

open access: yes, 2018
Objective: Stem cell-based tissue repair and regeneration require the regulation of cell migration and adhesion. As a regulator of cell polarization, Cdc42 (cell division control protein 42) plays a basic role at the initial stage of cell migration and ...
Ma, Liang   +15 more
core   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, Volume 13, Issue 57, 14 October 2026.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

The Effect of Cell Source on Mesenchymal Stem Cell Behavior and Osteogenic Differentiation of Buccal Fat Pad and Dental Pulp Stem Cells, an In Vitro Study [PDF]

open access: yes, 2022
Objective: The buccal fat pad is a source of adipose stem cells accessible from the oral cavity and dental pulp is a common dental source of stem cells.
Prisana Pripatnanont   +2 more
core   +1 more source

Comparative analysis of different feeder layers with 3T3 fibroblasts for culturing rabbits limbal stem cells [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To explore the possibility of human umbilical cord mesenchymal stem cells (hUCMSCs), human umbilical vein endothelial cells (hUVECs), human dental pulp stem cells (hDPSCs) and human periodontal ligament stem cells (hPDLSCs) serving as feeder cells ...
Hui-Xian Wang   +6 more
doaj   +1 more source

Isolation, propagation, and prion protein expression during neuronal differentiation of human dental pulp stem cells

open access: yes, 2019
Bioethical issues related to the manipulation of embryonic stem cells have hindered advances in the field of medical research. For this reason, it is very important to obtain adult stem cells from different tissues such as adipose, umbilical cord, bone ...
Sorice, Maurizio   +8 more
core   +1 more source

Effects of Two Calcium Silicate Cements on Transforming Growth Factor-β1 Secretion from Human Dental Pulp Stem Cells [PDF]

open access: yes, 2018
Introduction: The aims of this in vitro study were to evaluate the effects of two calcium silicate based cements, Calcum-enriched Mixture (CEM) and Biodentine  on proliferation of human dental pulp stem cells (hDPSCs) and the effects of proposed cements ...
Bagheri, Mehdi   +3 more
core   +1 more source

Human dental pulp stem cells differentiation: A review

open access: yesJournal of Craniomaxillofacial Research, 2018
The advent of regenerative medicine has brought us the opportunity to regenerate, modify and restore human organs function. Stem cells, a key resource in regenerative medicine, are defined as clonogenic, self-renewing, progenitor cells that can generate ...
Elham Mohammadi Golrang   +3 more
doaj  

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