Results 61 to 70 of about 12,768,039 (194)

Effects of Dentin Phosphophoryn-Derived RGD Peptides on the Differentiation and Mineralization of Human Dental Pulp Stem Cells In Vitro

Biomedicines, 2022
The purposes of this study were to investigate the in vitro effects of arginine-glycine-aspertic acid (RGD) peptides derived from human dentin phosphophoryn (DPP) on human dental pulp stem cell-proliferation, differentiation and mineralization, and to ...
Tubayesha Hassan, Youjing Qiu, Md Riasat Hasan, Takashi Saito   +3 more
doaj   +1 more source

Estudo da inervação na engenharia de tecido pulpar humano [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2015.Terapias regenerativas têm despertado o interesse no campo da ...
Coelho, Daniela Sousa
core  

Sustainable Effects of Human Dental Pulp Stem Cell Transplantation on Diabetic Polyneuropathy in Streptozotocine-Induced Type 1 Diabetes Model Mice

, 2021
Dental pulp stem cells (DPSCs) are suitable for use in regenerative medicine. Cryopreserved human DPSCs (hDPSCs) ameliorate diabetic polyneuropathy, and the effects of hDPSC transplantation are related to VEGF and NGF secretion.
Shogo Ozawa, Tatsuhito Himeno, Keiko Naruse, Shigemi Goto, Jun Takebe, Tasuku Ohno, Yuka Imanishi, Hideki Kamiya, Yasuko Kobayashi, Ken Miyazawa, Nobuhisa Nakamura, Mizuho Ito, Akio Mitani, Jiro Nakamura, Hitoshi Miyachi, Toru Nagao, Megumi Miyabe, Masaki Hata, Maiko Omi, Tatsuaki Matsubara   +19 more
core   +1 more source

Biological Function and Potential Applications of Garcinol in Human Dental Pulp Stem Cells [PDF]

, 2023
IntroductionThe regeneration of pulp tissue is crucial for true regenerative endodontic treatment, which requires a reduction in osteogenic differentiation. Garcinol, a histone acetyltransferase inhibitor, is a natural regulator that is known to suppress
Jang, Sunmi, Sumi Kang, Jung, Han-Sung, Kim, Sunil, Uk-Seong Kim, Kim, Euiseong, Sunil Kim, Chang, Insoon, Sukjoon Lee, Euiseong Kim, Kim, Uk-Seong, Shin, Su-Jung, Kang, Sumi, Han-Sung Jung, Lee, Sukjoon, Insoon Chang, Su-Jung Shin, Sunmi Jang   +17 more
core   +1 more source

Development of a Nano‐Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications—An In Vitro Study

International Endodontic Journal, Volume 59, Issue 9, Page 1936-1953, September 2026.
ABSTRACT Aim Hydraulic calcium silicate cements are widely employed in endodontics due to their excellent biocompatibility, bioactivity, sealing ability, and remineralisation potential. However, currently used products such as mineral trioxide aggregate (MTA) exhibit several limitations, including discolouration, cost, and poor handling properties ...
P. A. A. S. Prasad Kumara, Paul R. Cooper, Peter Cathro, Henry F. Duncan, Maree Gould, George Dias, Jithendra Ratnayake   +6 more
wiley   +1 more source

Blockade of PD-L1/PD-1 signaling promotes osteo-/odontogenic differentiation through Ras activation

International Journal of Oral Science, 2022
The programmed cell death ligand 1 (PD-L1) and its receptor programmed cell death 1 (PD-1) deliver inhibitory signals to regulate immunological tolerance during immune-mediated diseases.
So Mi Jeon, Je Sun Lim, Su Hwan Park, Hyung Joon Kim, Hyung-Ryong Kim, Jong-Ho Lee   +5 more
doaj   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, Volume 59, Issue 9, Page 1871-1886, September 2026.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source

A novel hypoxic lncRNA, HRL-SC, promotes the proliferation and migration of human dental pulp stem cells through the PI3K/AKT signaling pathway

Stem Cell Research & Therapy, 2022
Background Human dental pulp stem cells (hDPSCs) are critical for pulp generation. hDPSCs proliferate faster under hypoxia, but the mechanism by which long noncoding RNA (lncRNA) regulates this process is not fully understood.
Junkai Zeng, Ming Chen, Yeqing Yang, Buling Wu   +3 more
doaj   +1 more source

Naringenin stimulates osteogenic/odontogenic differentiation and migration of human dental pulp stem cells

Journal of Dental Sciences, 2023
Background/purpose: Naringenin, a naturally occurring flavanone in citrus fruits, regulates bone formation by bone marrow-derived mesenchymal stem cells. The purpose of this study was to characterize the effects of naringenin on some biological behaviors
Yeon Kim, Hyun-Joo Park, Mi-Kyoung Kim, Yong-Il Kim, Hyung Joon Kim, Soo-Kyung Bae, Jacques E. Nör, Moon-Kyoung Bae   +7 more
doaj   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

International Endodontic Journal, Volume 59, Issue 9, Page 1792-1803, September 2026.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad, Neda Najafimakhsoos, George Bogen   +2 more
wiley   +1 more source