Results 81 to 90 of about 12,768,039 (194)

Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells

Mediators of Inflammation, 2022
Dental pulp inflammation is a widespread public problem usually caused by caries or trauma. Alleviating inflammation is critical to inflamed pulp repair. Human β-defensin 1 short motif Pep-B is a cationic peptide that has anti-inflammatory, antibacterial,
Jue Shi, Zihe Hu, Yanyan Zhou, Minghao Zuo, Haiyan Wu, Wenjing Jin, Zhijian Xie   +6 more
doaj   +1 more source

Circ‐0030167/IGF2BP1 Induces Mitophagy‐Mediated Ferroptosis via HMOX1 mRNA Stabilization in Pancreatic Cancer

Cancer Science, Volume 117, Issue 5, Page 1362-1379, May 2026.
Our findings identify circ‐0030167/IGF2BP1/HMOX1 axis as a critical regulatory factor targeting mitochondria‐mediated ferroptosis, thereby presenting a novel therapeutic target for PC combination therapies. ABSTRACT Pancreatic cancer (PC) represents a highly aggressive malignancy characterized by a 5 year survival rate of less than 12%.
Qun Zhao, Xihao Yao, Jingjing Lu, Qiyang Chen, Zhiwei Wang, Xiaohong Li, Yuhua Lu   +6 more
wiley   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

In Vitro and In Vivo Dentinogenic Efficacy of Human Dental Pulp-Derived Cells Induced by Demineralized Dentin Matrix and HA-TCP

Stem Cells International, 2017
Human dental pulp cells have been known to have the stem cell features such as self-renewal and multipotency. These cells are differentiated into hard tissue by addition of proper cytokines and biomaterials. Hydroxyapatite-tricalcium phosphates (HA-TCPs)
Kyung-Jung Kang, Min Suk Lee, Chan-Woong Moon, Jae-Hoon Lee, Hee Seok Yang, Young-Joo Jang   +5 more
doaj   +1 more source

A Tutorial for Isolating, Characterizing, and Inducing Presenescence in Human Periodontal Ligament and Dental Pulp Stem Cells

Current Protocols, Volume 6, Issue 4, April 2026.
Abstract For several years, scientists have focused on studying mesenchymal stem cells because of their ability for self‐regeneration, their potential for differentiation into multiple lineages (e.g., osteogenic, chondrogenic, and adipogenic cells), and their low immunogenicity and remarkable capacity to modulate the immune system.
Kamila Sauer Veiga Leme, Márjorie de Assis Golim, Aline Márcia Marques Braz, Elenice Deffune, Daisy Maria Fávero Salvadori   +4 more
wiley   +1 more source

Photobiomodulation With 976 nm Diode Laser Enhances Osteoblastic Differentiation of Saos‐2 Cells Cultured on Collagen Membranes

Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objective Laser photobiomodulation (PBM) influences cellular proliferation, morphology, and differentiation. Collagen membranes provide a bioactive scaffold that supports osteoblastic behavior; however, the effects of PBM on preosteoblastic Saos‐2 cells cultured on these membranes remain unclear.
Escobar Lina M., Bendahan Zita, Pinzón Paula, Grajales Marggie, Baldion Paula   +4 more
wiley   +1 more source

Transdifferentiation of Human Dental Pulp Stem Cells Into Oligoprogenitor Cells [PDF]

, 2017
Introduction: The nerve fibers in central nervous system are surrounded by myelin sheet which is formed by oligodendrocytes. Cell therapy based on oligodendrocytes and their precursors transplantation can hold a promising alternative treatment for myelin
Hatef Ghasemi Hamidabadi, Esmaeilnejad-Moghadam, A., Ardeshir Moayeri, Maryam Nazm Bojnordi, Sara Haratizadeh, Bojnordi, M. N., Alizadeh, R., Amir Esmaeilnejad-Moghadam, Hamidabadi, H. G., Moayeri, A., Rafieh Alizadeh, Haratizadeh, S., null null   +12 more
core   +1 more source

Dysregulation of lncRNA TFAP2A‐AS1 is involved in the pathogenesis of pulpitis by the regulation of microRNA‐32‐5p

Immunity, Inflammation and Disease
Objective This study was designed to evaluate TFAP2A‐AS1 expression in the dental pulp of teeth with or without pulpitis and to determine the function of TFAP2A‐AS1 in pulp cells.
Mingming Liu, Weijing Jia, Lin Bai, Qiaolin Lin   +3 more
doaj   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, Volume 59, Issue 4, Page 590-613, April 2026.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Dental pulp derived mesenchymal stromal cells

This book presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.? In this thoroughly updated and expanded second edition, the author covers mesenchymal stem cell
Yildirim, Sibel
core   +1 more source