Results 271 to 280 of about 109,393 (302)

Antiphotoaging effect of chitooligosaccharides on human dermal fibroblasts

Photodermatology, Photoimmunology & Photomedicine, 2012
SummaryBackground/PurposeIn the present study, the effect of 3–5 kDa chitooligosaccharide (COS) on homeostasis between the expression of collagen‐degrading matrix metalloproteinases (MMPs) and collagen synthesis was investigated using ultraviolet (UV)‐A irradiated dermal fibroblasts.MethodsUV protection imparted by 3–5 kDa COS was measured by examining
Jung-Ae, Kim, Byul-Nim, Ahn, Chang-Suk, Kong, Sung-Ha, Park, Byoung-Jun, Park, Se-Kwon, Kim   +5 more
openaire   +2 more sources

Human Wound Healing Fibroblasts Have Greater Contractile Properties Than Dermal Fibroblasts

Journal of Surgical Research, 1994
Contractile and phenotypic properties of human fibroblasts from healing wounds were compared to those of dermal fibroblasts using in vitro models. Wound fibroblasts were recovered from implants, made of a polyvinyl alcohol sponge threaded into a perforated silicone tube, 12 days after their subcutaneous implantation in human volunteers.
L, Germain, A, Jean, F A, Auger, D R, Garrel   +3 more
openaire   +2 more sources

Isolation and Culture of Human Dermal Fibroblasts

Dermal fibroblasts are the main cell type present in skin connective tissue (dermis). They are responsible for the synthesis of dermal extracellular matrix (ECM), providing mechanical stability for the dermal layer. In addition, fibroblasts interact with epidermal cells during hair development and in interfollicular skin cells through bidirectional ...
Ziliani, Fabiana, Michalak-Micka, Katarzyna, Klar, Agnes S   +2 more
openaire   +2 more sources

Human normal dermal fibroblasts express somatostatin receptors.

Experimental dermatology, 1999
The hormone/neuropeptide somatostatin (SOM) exerts multiple functions in the central nervous system, the immune system, the hypothalamo-pituitary axis, the gastrointestinal tract, and the pancreas. Endogenous SOM occurs in 2 biologically active forms, with 14 or 28 amino acids. Five subtypes of SOM receptors have been cloned.
A, Gaudillère, C, Bernard, J, Abello, D, Schmitt, A, Claudy, L, Misery   +5 more
openaire   +2 more sources

Biological effects of cellular stretch on human dermal fibroblasts

Journal of Plastic, Reconstructive & Aesthetic Surgery, 2013
Pathological scars are fibroproliferative skin disorders that are characterised by the accumulation of fibroblasts and collagens. It is increasingly understood that their development and progression may be related to local skin mechanics, such as stretching.
Chenyu, Huang, Kunio, Miyazaki, Satoshi, Akaishi, Atsushi, Watanabe, Hiko, Hyakusoku, Rei, Ogawa   +5 more
openaire   +2 more sources

Matrix metalloproteinase expression in cytokine stimulated human dermal fibroblasts

Burns, 2003
In this study, we investigated the effect of inflammatory cytokines on matrix metalloproteinase (MMP-1) and TIMP-1 production in human dermal fibroblasts, which play a pivotal role in wound healing, ranging from the synthesis and remodeling of extracellular matrix (ECM) to the synthesis of growth factors.
Mohan R K, Dasu, Robert E, Barrow, Marcus, Spies, David N, Herndon   +3 more
openaire   +2 more sources

Smads regulate collagen gel contraction by human dermal fibroblasts

British Journal of Dermatology, 2003
Transforming growth factor (TGF)-beta induces fibroblast contraction that is implicated in efficient wound healing. The Smad family of proteins mediates signal transduction of the TGF-beta superfamily. However, its role in fibroblast contraction remains unclear.To determine whether Smad proteins regulate fibroblast contraction.We used an in vitro type ...
K, Sumiyoshi, A, Nakao, Y, Setoguchi, K, Okumura, R, Tsuboi, H, Ogawa   +5 more
openaire   +2 more sources

Chitooligosaccharides attenuate UVB-induced damages in human dermal fibroblasts

Naunyn-Schmiedeberg's Archives of Pharmacology, 2011
As a continuation of our research on chitooligosaccharides (COS), this study focused on the protective effect of COS of various molecular weights (1-3, 3-5, and 5-10 kDa) on cellular damage caused by ultraviolet B (UVB)-induced oxidative stress in human dermal fibroblast cells.
Ahn, Byul-Nim, Kim, Jung-Ae, Himaya, S. W. A., Bak, Soon-Sun, Kong, Chang-Suk, Kim, Se-Kwon   +5 more
openaire   +3 more sources

Electrical Stimulation Increases Random Migration of Human Dermal Fibroblasts

Annals of Biomedical Engineering, 2017
Exogenous electrical stimulation (ES) has been investigated as a therapy for chronic wounds, as the skin produces currents and electrical fields (EFs) during wound healing. ES therapies operate by applying small EFs to the skin to mimic the transepithelial potentials that occur during the granulation phase of wound healing.
Sarah, Snyder, Carlisle, DeJulius, Rebecca Kuntz, Willits   +2 more
openaire   +2 more sources

Human dermal fibroblasts express multiple bFGF and aFGF proteins

In Vitro Cellular & Developmental Biology - Animal, 1991
We investigated the regulation of expression of bFGF and aFGF in cultures of normal human dermal fibroblasts grown in a defined, serum-free medium which did not contain FGF. Under these conditions we detected three molecular weight forms of bFGF protein [18.0, 23.0, and 26.6 kiloDaltons (kD)] and three molecular weight forms of aFGF protein (18.4, 19.2,
L L, Root, G D, Shipley
openaire   +2 more sources