Results 21 to 30 of about 31,425 (209)

Human epididymis protein 4-annexin II binding promotes aberrant epithelial-fibroblast crosstalk in pulmonary fibrosis [PDF]

Communications Biology
Invasive lung myofibroblasts are the main cause of tissue remodeling in idiopathic pulmonary fibrosis (IPF). A key mechanism contributing to this important feature is aberrant crosstalk between the abnormal/injured lung epithelium and pulmonary ...
Weishuai Zheng, Menglin Zou, Xingxing Hu, Han Gao, Weiwei Song, Qinhui Hou, Yuan Liu, Zhenshun Cheng   +7 more
doaj   +2 more sources

Serum Human Epididymis Protein 4 is a Potential Biomarker for Early Chronic Kidney Disease in an Obese Population

Diabetes, Metabolic Syndrome and Obesity, 2021
Shubo Tan, Yongmao Zeng, Shiliang Kuang, Jianjun Li Department of Urology, Second Affiliated Hospital of the University of South China, Hengyang City, 421000, People’s Republic of ChinaCorrespondence: Jianjun LiDepartment of Urology, Second ...
Tan S, Zeng Y, Kuang S, Li J
doaj   +2 more sources

Role of Human Epididymis Protein 4 (HE4) in Determining Survival of Patients With Endometrial Cancer: A Meta-Analysis

Technology in Cancer Research & Treatment, 2020
Background: Human epididymis protein 4 (HE4) is a novel cancer biomarker. This study evaluates the prognostic role of HE4 in determining the survival of endometrial cancer patients. Methods: Literature search was conducted in electronic databases (Embase,
Ying He MD, Jing Wang MD, Chun-Xing Ma MD, Yan-Hua Kang MD   +3 more
doaj   +2 more sources

Clinical significance of serum human epididymis protein 4 in liver fibrosis: An experimental study. [PDF]

Medicine (Baltimore), 2020
Abstract Background: Human epididymis protein 4 (HE4) has been identified as marker for renal fibrosis. Present study aimed to investigate the clinical significance of serum HE4 in liver fibrosis. Methods: Serum from 65 liver fibrosis patients, 68 hepatic patients without ...
Hou Y, Li F, Chen J, Zhao J, Li D, Chen H.   +5 more
europepmc   +3 more sources

MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension [PDF]

Cardiovascular Therapeutics, 2022
Background. Pulmonary arterial hypertension (PAH) usually causes right ventricular dysfunction, which is closely related to cardiac fibrosis. But cardiac fibrosis mechanism remains unclear.
Yi Tang, Xiaowei Huo, Junyu Liu, Yijin Tang, Min Zhang, Wenlin Xie, Zhaofen Zheng, Jin He, Jiayan Lian   +8 more
doaj   +2 more sources

Association Between Serum Human Epididymis Protein 4 Levels and Cardiovascular Events in Obese Patients with Breast Cancer [PDF]

Diabetes, Metabolic Syndrome and Obesity, 2021
Li Wang,1 Nie Hu,1 Zhongjun Jiang,1 Ping Luo,1 Nian Yi,1 Yanhua Chen,2 Ning Zhou,2 Longfei Liu2 1Department of Breast Surgery, Nanhua Hospital, Nanhua University, Hengyang City, Hunan Province, 421002, People’s Republic of China; 2Department of General ...
Wang L, Hu N, Jiang Z, Luo P, Yi N, Chen Y, Zhou N, Liu L   +7 more
doaj   +2 more sources

Increased serum human epididymis protein 4 is associated with disease activity and systemic involvement in pediatric-onset systemic lupus erythematosus. [PDF]

Front Immunol
Liu C, Yan L, Zhang M, Duan Y, Luo J, Liu Z, Liu T, Tong J, Jiang Y.   +8 more
europepmc   +2 more sources

Human Epididymis Protein 4 in Transcatheter Aortic Valve Implantation: Diagnostic and Prognostic Value. [PDF]

JACC Adv
Giuliani C, Zanuttini A, Nuche J, Farjat Pasos JI, Bernard J, Lionel T, Jacob S, Abu-Alhayja'a R, Beaudoin J, Côté N, DeLarochellière R, Paradis JM, Clavel MA, Arsenault BJ, Rodés-Cabau J, Pibarot P, Hecht S.   +16 more
europepmc   +2 more sources

Is serum human epididymis protein 4 ready for prime time? [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2013
The National Institute for Health and Clinical Excellence (NICE) guidelines have sparked hot debate regarding the role of carbohydrate antigen 125 (CA-125) for ovarian cancer (OC) detection. Recent literature and evidence calls into question the use of CA-125 in diagnostic algorithms, given the better performance of human epididymis protein 4 (HE4) vs.
S. Ferraro, M. Panteghini
openaire   +2 more sources

HE4 level in ascites may assess the ovarian cancer chemotherapeutic effect

Journal of Ovarian Research, 2018
Background The clinical treatment of ovarian cancer with ascites is problematic. The main reasons for treatment failure are the susceptibility to intraperitoneal metastasis and chemotherapeutic drug resistance.
Duanyang Liu, Dan Kong, Jing Li, Lei Gao, Di Wu, Yu Liu, Weiwei Yang, Lei Zhang, Jiang Zhu, Xiaoming Jin   +9 more
doaj   +1 more source