Results 1 to 10 of about 4,477 (231)

Determination of reference intervals of serum levels of human epididymis protein 4 (HE4) in Chinese women. [PDF]

J Ovarian Res, 2015
The detailed numbers of subjects from different centers.
Tian Y, Wang C, Cheng L, Zhang A, Liu W, Guo L, Ye H, Huang Y, Chen J, Wen X, Xing Y, Zheng G, Sun Z, Li H, Zhang P, Liu W, Chen Y, Zhang Z, Xu Y, Huo Y, Ou Q.   +20 more
europepmc   +7 more sources

Role of Human Epididymis Protein 4 (HE4) in Determining Survival of Patients With Endometrial Cancer: A Meta-Analysis [PDF]

Technology in Cancer Research & Treatment, 2020
Background: Human epididymis protein 4 (HE4) is a novel cancer biomarker. This study evaluates the prognostic role of HE4 in determining the survival of endometrial cancer patients. Methods: Literature search was conducted in electronic databases (Embase,
Ying He MD, Jing Wang MD, Chun-Xing Ma MD, Yan-Hua Kang MD   +3 more
doaj   +6 more sources

Serum Human Epididymis Protein-4 (HE4) - A novel Approach to Differentiate Malignant Frombenign Breast Tumors. [PDF]

Asian Pac J Cancer Prev, 2021
Background: The lack of sensitivity and specificity of existing diagnostic markers like Carbohydrate Antigen 15-3(CA15-3) and Carcinoembryonic antigen (CEA) in breast cancer stimulates the search for new biomarkers to improve diagnostic sensitivity ...
Sai Baba KSS, Rehman MA, Pradeep Kumar J, Fatima M, Raju GSN, Uppin SG, Mohammed N.   +6 more
europepmc   +5 more sources

Human epididymis protein 4 (HE4) in benign and malignant diseases [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2012
Background: Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign ...
Anastasi, Anastasi, Andersen, Andersen, Bast, Bast, Drapkin, Drapkin, Duffy, Duffy, Escudero, Escudero, Galgano, Galgano, Heintz, Heintz, Hellstrom, Hellstrom, Hellstrom, Hellstrom, Holcomb, Holcomb, Huhtinen, Huhtinen, Jacob, Jacob, Jacobs, Jacobs, Kurman, Kurman, Liu, Liu, Montagnana, Montagnana, Moore, Moore, Nolen, Nolen, Tuxen, Tuxen   +39 more
core   +6 more sources

Elevated level of serum human epididymis protein 4 (HE4) predicts disease severity and mortality in COVID-19 pneumonia. [PDF]

BMC Pulm Med, 2023
Background We retrospectively analyzed serum level of human epididymis protein 4 (HE4) as a pulmonary inflammatory biomarker in patients with COVID-19 pneumonia in association with disease severity and outcome.
Sütő R, Pócsi M, Szabó Z, Fejes Z, Ivády G, Kerekes G, Fagyas M, Nagy A, Szentkereszty Z, Kappelmayer J, Nagy B.   +10 more
europepmc   +5 more sources

Human epididymis protein 4 (HE4) is a novel biomarker for fibrosis in IgG4-related disease and can predict poor prognosis [PDF]

RMD Open, 2022
Objectives IgG4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory disorder with heterogeneous manifestations. This study aimed to investigate the utility of human epididymis protein 4 (HE4) as a potential clinical biomarker of fibrosis in
Wen Zhang, Yongzhe Li, Yuan Huang, Songxin Yan, Yu Peng, Hui Lu, Ziyan Wu, Shengwei Mo, Xianlong Chen, Xiaomeng Li   +9 more
doaj   +3 more sources

The Diagnostic Accuracy of Serum and Urine Human Epididymis Protein 4 (HE4) in Ovarian Cancer in 15,394 Subjects: An Updated Meta-Analysis. [PDF]

Cureus, 2022
Background We aim to determine the diagnostic accuracy of both serum and urinary human epididymis protein 4 (HE4) in the diagnosis of ovarian cancer. Methods Electronic databases and search engines such as PubMed, Cochrane Library, and Google Scholar ...
Nalini N, Kumar A, Sharma S, Singh B, Singh AV, Prakash J, Singh S.   +6 more
europepmc   +2 more sources

Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells. [PDF]

Front Pharmacol, 2021
Decreased human epididymis protein 4 (HE4) plasma levels were reported in cystic fibrosis (CF) patients under CFTR potentiator ivacaftor therapy, which inversely correlated with lung function improvement.
Bene Z, Fejes Z, Szanto TG, Fenyvesi F, Váradi J, Clarke LA, Panyi G, Macek M, Amaral MD, Balogh I, Nagy B.   +10 more
europepmc   +2 more sources

The Role of Interleukin 6 (IL6), Cancer Antigen-125 (CA-125), and Human Epididymis Protein 4 (HE4) to predict tumor resectability in the advanced epithelial ovarian cancer patients. [PDF]

PLoS One, 2023
Introduction A study of tumor resectability in pre-operative patients with advanced epithelial ovarian cancer is required to predict primary surgical benefits accurately.
Muhammad S, Azwan RJ, Rita RS, Susanti R, Yusrawati.   +4 more
europepmc   +2 more sources

Elevation of serum human epididymis protein 4 (HE4) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) as predicting factors for the occurrence of acute kidney injury on chronic kidney disease: a single-center retrospective self-control study. [PDF]

Front Pharmacol, 2023
Objectives: To evaluate whether novel biomarkers of renal injury, serum HE4 and NT-proBNP could predict acute kidney injury (AKI) on chronic kidney disease (CKD) (A on C) and assess the specificity and efficiency of serum creatinine (SCr), HE4 and NT ...
Song J, Chen L, Yuan Z, Gong X.
europepmc   +2 more sources