Results 91 to 100 of about 4,477 (231)

Comparison of the Serum Level of Cancer Antigen 125 and Human Epididymis Protein 4 in Ovarian Cancer Patients and Healthy Groups in Isfahan City

Advanced Biomedical Research, 2017
Background: Ovarian cancer is the most common fatal malignancy of the gynecology tract. The purpose of this study was to compare serum levels of tumor markers cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) in both healthy groups and ...
Mahnaz Bakrani, Kahin Shahani Poor, Valiollah Mehrzad, Nematallah Razmi   +3 more
doaj   +1 more source

Human epididymis protein 4: a novel predictor of ischemic cardiomyopathy

BMC Cardiovascular Disorders, 2021
Background The prognostic value of human epididymis protein 4 (HE4) in patients with ischemic cardiomyopathy (ICM) is unknown. Methods A total of 103 patients with ICM were prospectively enrolled in this study from Hunan Provincial People’s Hospital ...
Yi Tang, Yinzhen Wang, Xiaoping Xu, Laura Yan Tu, Pei Huang, Xiaoyan Yang, Lihua Li, Juan Wu, Yan Zhang, Qinghua Fu, Yingli Yu, Zhaofen Zheng, Lixia Song, Yi Zhang   +13 more
doaj   +1 more source

Change-point of multiple biomarkers in women with ovarian cancer [PDF]

, 2017
To date several algorithms for longitudinal analysis of ovarian cancer biomarkers have been proposed in the literature. An issue of specific interest is to determine whether the baseline level of a biomarker changes significantly at some time instant ...
Blyuss, O, Dawnay, A, Gentry-Maharaj, A, Jacobs, I, Kalsi, J, Mariño, IP, Menon, U, Ryan, A, Timms, JF, Zaikin, A   +9 more
core   +1 more source

Tissue expression of human epididymal secretory protein 4 may be useful in the differential diagnosis of uterine cervical tumors [PDF]

, 2017
Objectives: Human Epididymal Secretory Protein 4 was firstly described as an epididymis-specific protein but more recently it has been demonstrated to be a putative serum tumor marker for different malignancies, especially ovarian epithelial cancers. The
Akata, Talya, Akman, Tulay, Ayaz, Duygu, Aydiner, Fatma, Diniz, Gulden, Karadeniz, Tugba, Sayhan, Sevil, Solakoglu Kahraman, Dudu   +7 more
core   +2 more sources

Effectiveness of human epididymis protein 4 (HE4) as predictor of response to first line platinum based chemotherapy

European Journal of Gynaecological Oncology, 2021
Objective: To assess the role of HE4 (Human epidydimal protein 4) marker as predictor of response to platinum based chemotherapy. Methods: In the current observational prospective study, 35 patients affected by High Grade Serous Ovarian Cancer (HGSOC) were enrolled; among these, 17 patients were platinum sensitive, while 18 were platinum resistant. HE4
Plotti F., Bartolone M., Terranova C., Guzzo F., de Cicco Nardone C., Montera R., Molinaro M., Ciccozzi M., Benvenuto D., Di Donato V., Benedetti Panici P., Angioli R.   +11 more
openaire   +1 more source

A Case Report of Aggressive Angiomyxoma in the Buttock of a Female

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Aggressive angiomyxoma presents distinctive MRI features like “whirl sign” and “layering sign.” Laparoscopic combined with perianal incision can minimize bleeding and organ damage risks for pelvic‐extending tumors. Surgical excision with negative pressure drainage aids wound healing. Long‐term follow‐up is crucial to prevent recurrence.
Aiwen Le, Zhibin Zheng, Tong Wu
wiley   +1 more source

Serum HE4 is more suitable as a biomarker than CA125 in Chinese women with benign gynecologic disorders [PDF]

, 2014
Objective: This study measured the human epididymis protein 4 (HE4) and CA125 levels in Chinese women with benign gynecological disorders.Material and methods: Sera were obtained from Chinese women prior to surgery for a pelvic mass and HE4 and CA125 ...
Li, L, Li, Y, Qiao, C, Zhang, Y, Zhao, X
core   +2 more sources

Management of COPD With Cardiovascular Risk in Asia: A Review by the Asian Pacific Society of Respirology COPD Assembly

Respirology, Volume 30, Issue 9, Page 817-830, September 2025.
ABSTRACT Chronic obstructive pulmonary disease (COPD) has a high burden in Asia. These patients are also susceptible to various cardiovascular diseases (CVD). A panel of expert Asian pulmonologists explored the published literature to understand the impact of COPD and CVD on each other and to identify the cardiopulmonary risk factors in the region. The
Chin Kook Rhee, Fanny Wai San Ko, Vu Van Giap, Theerasuk Kawamatawong, Jung‐Kyu Lee, Kazuto Matsunaga, Helmy Haja Mydin, Yong‐Kek Pang, Diahn‐Warng Perng, Myla Salazar‐Supe, Yoko Shibata, David Sim, Naoya Tanabe, Augustine Tee, Hao‐Chien Wang, Yen‐Wen Wu, Faisal Yunus   +16 more
wiley   +1 more source

Prospective evaluation of 92 protein biomarkers for early detection of endometrial cancer

International Journal of Cancer, Volume 157, Issue 3, Page 480-489, 1 August 2025.
What's new? In this prospective study, the authors evaluated the discrimination capacity of 92 cancer‐related proteins as potential early detection biomarkers for endometrial cancer using blood samples from two large‐scale European population cohorts (EPIC and Janus).
Victoria Cooley, Renée Turzanski Fortner, Trasias Mukama, Sabine Naudin, Valeria Pala, Laure Dossus, Inger T. Gram, Karina Standahl Olsen, Maria‐Jose Sánchez, Pernilla Israelsson, Naomi Allen, Hilde Langseth, Rudolf Kaaks   +12 more
wiley   +1 more source

HE-4 in the Diagnosis of Carcinoma of Ovary Presented as Unknown primary Carcinoma: A Case Report

Journal of Investigative Medicine High Impact Case Reports
Ovarian cancer is the second most common gynecologic malignancy in the United States, with high mortality due to delayed diagnosis. Serum CA-125 is widely used for screening and monitoring but lacks sensitivity and specificity in some cases. We present a
Shengmin Huang MD, Muhammad Tahir MD, Gardith Joseph MD, Richrd Wu MD, Jaron Tepper MD, Jen C. Wang MD   +5 more
doaj   +1 more source