Results 111 to 120 of about 4,477 (231)

Comprehensive analysis of the value of angiogenesis and stemness‐related genes in the prognosis and immunotherapy of ovarian cancer

open access: yesBioFactors, Volume 51, Issue 1, January/February 2025.
Tumor angiogenesis and the presence of cancer stem cells (CSCs) are critical characteristics of tumors. In this study, we utilized cluster analysis and LASSO methods to assess the significance of angiogenesis‐ and stemness‐related genes in the efficacy of oncolytic virus (OV) immunotherapy.
Linsen Zhou   +5 more
wiley   +1 more source

Clinical analysis of four serum tumor markers in 458 patients with ovarian tumors: diagnostic value of the combined use of HE4, CA125, CA19-9, and CEA in ovarian tumors

open access: yesCancer Management and Research, 2018
Fawen Chen,1,2 Jing Shen,3 Jianwei Wang,1 Pengwei Cai,1 Yi Huang3 1Department of Clinical Laboratory, Fujian Provincial Hospital South Branch, 2Department of Blood Transfusion, 3Department of Clinical Laboratory, Fujian Provincial Hospital, Provincial ...
Chen F, Shen J, Wang J, Cai P, Huang Y
doaj  

Wartość diagnostyczna CA125, HE4, ROMA oraz modelu regresji logistycznej w diagnistyce guzów miednicy mniejszej – doświadczenia własne [PDF]

open access: yes, 1970
Objectives: The aim of this study was to compare and evaluate the quality of CA125, HE4, logistic regression model based on CA125 and HE4, and ROMA algorithm in preoperational differential diagnostics of the ovarian tumors.
Gąsiorowska, Emilia   +2 more
core   +2 more sources

Genital Tuberculosis and Serous Cystadenoma in a 58‐Year‐Old Female With Rheumatoid Arthritis and Sjögren’s Syndrome: A Case Report

open access: yesCase Reports in Rheumatology, Volume 2025, Issue 1, 2025.
Genital tuberculosis (GT) is a rare but significant extrapulmonary tuberculosis form, often mimicking ovarian malignancy. We report a case of a 58‐year‐old woman with Sjögren’s syndrome and rheumatoid arthritis, previously treated with infliximab, who presented with abdominal distension, weight loss, night sweats, and intermittent abdominal pain ...
Sheila De la Cruz-Aragón   +6 more
wiley   +1 more source

Correlation of Human Epididymis Protein 4 Expression with Clinicopathologic Parameters in Gastric Carcinomas

open access: yesHamidiye Medical Journal
Background: Human epididymis protein 4 (HE4) was discovered in 1991 as a glycoprotein secreted from the cells of the human epididymal epithelium and associated with sperm development and immunity.
Pınar Öksüz   +4 more
doaj   +1 more source

Altered glycosylation in cancer: molecular functions and therapeutic potential

open access: yesCancer Communications, Volume 44, Issue 11, Page 1316-1336, November 2024.
Abstract Glycosylation, a key mode of protein modification in living organisms, is critical in regulating various biological functions by influencing protein folding, transportation, and localization. Changes in glycosylation patterns are a significant feature of cancer, are associated with a range of pathological activities in cancer‐related processes,
Xuemeng Xu   +17 more
wiley   +1 more source

Sensitive and Cost‐Effective Tools in the Detection of Ovarian Cancer Biomarkers

open access: yesAnalytical Science Advances, Volume 5, Issue 9-10, October 2024.
ABSTRACT Women diagnosed with late‐stage ovarian cancer suffer a very high rate of mortality. Accordingly, it is imperative to detect and diagnose the disease as early as possible in its development. Achievement of this aim implies relatively large‐scale screening of women at an age of clinical significance through assay of biomarkers for disease ...
Anis Elhami   +6 more
wiley   +1 more source

Human epididymis protein 4-annexin II binding promotes aberrant epithelial-fibroblast crosstalk in pulmonary fibrosis

open access: yesCommunications Biology
Invasive lung myofibroblasts are the main cause of tissue remodeling in idiopathic pulmonary fibrosis (IPF). A key mechanism contributing to this important feature is aberrant crosstalk between the abnormal/injured lung epithelium and pulmonary ...
Weishuai Zheng   +7 more
doaj   +1 more source

Development of Follicle-Stimulating Hormone Receptor Binding Probes to Image Ovarian Xenografts [PDF]

open access: yes, 2015
The Follicle-Stimulating Hormone Receptor (FSHR) is used as an imaging biomarker for the detection of ovarian cancer (OC). FSHR is highly expressed on ovarian tumors and involved with cancer development and metastatic signaling pathways.
Guo, Lili   +3 more
core   +1 more source

Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer

open access: yesThe Clinical Respiratory Journal
Objective This study aimed to explore the application value of human epididymis protein 4 (HE4) in diagnosing and monitoring the prognosis of lung cancer.
Tingting Zhang   +4 more
doaj   +1 more source

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