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Human epididymis protein 4 (HE4) in laboratory medicine and an algorithm in renal disorders.

Clinica Chimica Acta, 2015
Over the past three decades, cancer antigen (CA) 125 has been utilized for monitoring women who were treated for ovarian cancer. However, this tumor marker showed several limitations such as false elevation in benign pelvic diseases and, in turn, no alterations in ovarian tumors at early stages with a relatively high ratio. For more than ten years, the
J. Kappelmayer   +2 more
semanticscholar   +3 more sources

Evaluating the expression and diagnostic value of human epididymis protein 4 (HE4) in small cell lung cancer

open access: yesTumor Biology, 2014
We evaluated the expression and diagnostic value of human epididymis protein 4 (HE4) in small cell lung cancer (SCLC). Serum HE4 level was measured in serum samples from 30 healthy controls and 49 patients with SCLC using enzyme-linked immunosorbent assay. HE4 expression in tumor tissues was analyzed by immunohistochemical staining.
Ximing Wang   +4 more
semanticscholar   +3 more sources

Serum human epididymis protein 4 (HE4) levels in colorectal cancer patients.

Journal of Clinical Oncology, 2015
e14650 Background: Tumour markers are widely used for diagnosis, staging, and monitoring colorectal cancer (CRC) patients in clinical practice.
Yasemin Kemal   +7 more
openaire   +2 more sources

Human epididymis secretory protein 4 in serum (HE4) as a marker of ovarian cancer

Journal of Clinical Oncology, 2008
16554 Background: CA125 is the most widely used biochemical marker for detection of ovarian cancer. However, it is also frequently elevated in women with commonly diagnosed benign disease.
K. Z. Qu   +4 more
openaire   +1 more source

Clinical significance of human epididymis protein 4 (HE4), cancer antigen 125 (CA125), the risk of ovarian malignancy algorithm (ROMA), and Copenhagen index (CPH-I) for the diagnosis of endometrial carcinoma.

Folia Medica
INTRODUCTION Endometrial carcinoma (EC) is the most common gynecological cancer among women, and in more than 90% of cases, the initial manifestation of the disease is postmenopausal bleeding.
Vesselina Koleva   +2 more
semanticscholar   +1 more source

EP464 Relation between Human Epididymis Protein 4 (HE4) and endometrial pathology in patients with postmenopausal bleeding

ePoster, 2019
Introduction/Background To evaluate the value of human epididymis protein 4 (HE4) in predicting endometrial pathology in patients with postmenopausal bleeding (PMB). Methodology 100 patients with PMB were recruited with endometrial thickness (ET) >5 mm by transvaginal sonography(TVS).HE4 was measured and hysteroscopic guided fractional curretage (FC)
A Aboulnasr   +4 more
openaire   +1 more source

Serum Human Epididymis Secretory Protein 4 (HE4) is a Potential Prognostic Biomarker in Non-Small Cell Lung Cancer

Clinical Laboratory, 2018
Human epididymis secretory protein 4 (HE4) is a secreted glycosylated protein belonging to the WFDC family, which is an ideal biomarker in ovarian cancer. However, the role of HE4 in lung cancer is still unclear. The study aimed to evaluate serum levels of HE4 as a prognostic biomarker in patients with non-small cell lung cancer (NSCLC).The subjects ...
Dongping, Mo, Fang, He
openaire   +2 more sources

Does Human Epididymis Protein 4 (HE4) Have a Role in Prediction of Recurrent Epithelial Ovarian Cancer

2016
Asian Pacific Journal of Cancer Prevention, 17 ...
Pedrada Innao   +1 more
openaire   +1 more source

Comparison between human epididymis protein 4 (HE4) and CA125 in early-stage endometrial cancer.

2015
Comparison between human epididymis protein 4 (HE4) and CA125 in early-stage endometrial ...
MONTAGNANA, Martina   +10 more
openaire   +2 more sources

Human epididymis protein 4 (HE4): a potential biomarker for IPF

Molecular pathology and funct. genomics, 2020
Sung Jo   +5 more
openaire   +1 more source

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