Results 21 to 30 of about 4,477 (231)

Assessment of Human Epididymis Protein 4 Expression in Breast Ductal Carcinoma In Situ [PDF]

Diagnostics
Background/Objectives: Elevated expression of human epididymis protein 4 (HE4) has been observed in breast cancer and is associated with cancer progression; however, its role in ductal carcinoma in situ (DCIS) remains unclear.
Nah Ihm Kim, Min Ho Park, Ji Shin Lee
doaj   +2 more sources

The level of human epididymis protein 4 is associated with poor prognosis in patients with ejection fraction preserved heart failure [PDF]

Frontiers in Cardiovascular Medicine
IntroductionThe prognostic value of human epididymis protein 4 (HE4) in patients with heart failure with preserved ejection fraction (HFpEF) is unknown.MethodsPatients diagnosed with HFpEF in the Department of Cardiovascular Medicine of Hunan Provincial ...
Yi Tang, Yu Chen, Xiao Jiao Huang, Zheng Qi Hu, Yon Jun Hu, Si-ling Peng, Hong-wei Pan   +6 more
doaj   +2 more sources

Prognostic Value of Human Epididymis Protein 4 in Acute Myocardial Infarction [PDF]

International Journal of General Medicine
Yi Tang,1,* Wen-Yu Zhu,2,* Si-Ling Peng,2,* Shuai Huang,2,* Qiu-Ni Zhao,3 Si-Yuan Tan,2 Zi-Hui Yin,2 Yan Zhang,1 Jian-Qiang Peng,1 Hong-Wei Pan1 1Department of Cardiology, Hunan Provincial People’s Hospital, The First Affiliated Hospital ...
Tang Y, Zhu WY, Peng SL, Huang S, Zhao QN, Tan SY, Yin ZH, Zhang Y, Peng JQ, Pan HW   +9 more
doaj   +2 more sources

Diagnostic Value of Novel Biomarker Human Epididymis Protein 4 (HE4) in Detecting Endometrial Cancer [PDF]

International Journal of Women's Health and Reproduction Sciences, 2016
Objectives: Endometrial cancer (EC) is the most common malignancy of the female reproductive system. To date, no good marker for screening or disease monitoring of EC is available.
Mehri Jafari-Shobeiri, Marzye Jangi, A. Tabrizi, M. Sayyah-Melli, Parvin Mostafa-Gharabaghi, E. Ouladsahebmadarek, Esmail Neginfar, Y. Pouraliakbar, A. Çevirme, Y. Hamlaci, Kevser Ozdemir   +10 more
semanticscholar   +2 more sources

Human Epididymis Protein 4 (HE4) as a promising biomarker and therapy target in fibrotic diseases: A review

Journal of Holistic Integrative Pharmacy
The treatment of fibrosis faces a significant challenge due to the lack of effective therapies that can reverse established fibrosis. Early detection is vital for intervention, yet distinguishing fibrosis from normal tissue repair is complex.
Huiqun Tian, Li Chen
doaj   +2 more sources

The utility of serum human epididymis protein 4 (HE4) in patients with a pelvic mass [PDF]

Journal of Clinical Laboratory Analysis, 2009
AbstractAim: Although CA125 is the most widely used cancer marker in the diagnostic approach of pelvic masses in women, its clinical usefulness is limited because it lacks expression of the antigen in the early stages of disease. The human epididymis protein 4 (HE4) is frequently over‐expressed in ovarian cancer, whereas its expression in normal ...
M. Montagnana, G. Lippi, O. Ruzzenente, Valentina Bresciani, E. Danese, Silvia Scevarolli, G. Salvagno, S. Giudici, M. Franchi, G. Guidi   +9 more
semanticscholar   +4 more sources

Serum human epididymis protein 4 (HE4) as a tumor marker in men with lung cancer [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2014
Human epididymis protein 4 (HE4) is a reliable tumor marker for ovarian cancer, but only limited data are available on HE4 levels in lung malignancies.HE4 levels were measured at diagnosis in 98 men with lung cancer at different stages of the disease, and these results were compared to an age-matched healthy male cohort (n=98).
B. Nagy, H. Bhattoa, Z. Steiber, Mária Csobán, M. Szilasi, G. Méhes, Monika Müller, J. Lazar, J. Kappelmayer, P. Antal-Szalmas   +9 more
semanticscholar   +3 more sources

The diagnostic accuracy of human epididymis protein 4 (HE4) for discriminating between benign and malignant pelvic masses: a systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, 2021
Many women with benign pelvic masses, suspected of ovarian cancer, are unnecessarily referred for treatment at specialized centers. There is an unmet clinical need to improve diagnostic assessment in these patients.
M. Olsen, P. Lof, A. Stiekema, D. van den Broek, E. Wilthagen, P. Bossuyt, C. Lok   +6 more
semanticscholar   +1 more source

Serum Human Epididymis Protein 4 as a Novel Biomarker in Identifying Patients With Interstitial Lung Disease in Rheumatoid Arthritis

Frontiers in Medicine, 2021
Objective: Human epididymis protein 4 (HE4) have been implicated in the pulmonary involvements. We aimed to investigate the clinical utility of HE4 in clinical stratification in patients with rheumatoid arthritis (RA).Methods: This study included a ...
Liu Liang, Liu Liang, Jiali Chen, Chun Di, Minghua Zhan, Huizhang Bao, Changsheng Xia, Chunhong Fan, Yudong Liu   +8 more
doaj   +1 more source

Detection of Human Epididymis Protein 4 (HE4) in Human Serum Samples Using a Specific Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assay (ELISA). [PDF]

J Clin Lab Anal, 2016
Zhou L, Lv Z, Shao J, Xu Y, Luo X, Zhang Y, Hu Y, Zhang W, Luo S, Fang J, Wang Y, Duan C, Huang R.   +12 more
europepmc   +2 more sources