Results 31 to 40 of about 4,477 (231)
The diagnostic value of human epididymis protein 4 for endometrial cancer is moderate
Scientific Reports, 2021 Human epididymis protein 4 (HE4) has been used as a biomarker of endometrial cancer (EC) in clinical practice. However, there remains a lack of systemic research on the critical values of HE4 for diagnosing different clinical stages and pathological ...
Jing Liu, Lili Han, Zhen Jiao
doaj +1 more source
Current Oncology, 2022 Low-grade stage I endometrioid endometrial carcinomas should have an excellent prognosis, but a small subset of these cancers can relapse. The search for putative immunohistochemical prognostic markers for relapse in low-risk/low-grade endometrioid ...
Valerio Mais +8 more
doaj +1 more source
Ginekologia Polska, 2022 OBJECTIVES To compare utility of CA125, human epididymis protein 4 (HE4), risk of ovarian malignancy algorithm (ROMA), risk of malignancy index (RMI) and subjective assessment (SA) in preoperative diagnosis of ovarian tumors.
L. Janas +7 more
semanticscholar +1 more source
Serum human epididymis protein 4 (HE4) may be a better tumor marker in early lung cancer. [PDF]
Clinica Chimica Acta, 2016 Human epididymis protein 4 (HE4) had been shown to be an ideal biomarker in ovarian cancer. However, there were fewer reports on its application in lung cancer. We explored the diagnostic value of serum HE4 as a biomarker in early lung cancer by comparing it with other biomarkers.162 individuals including 112 cases of lung cancer at early stage and 50 ...
Qian Zeng +4 more
semanticscholar +3 more sources
Current clinical application of serum biomarkers to detect and monitor ovarian cancer – update
Menopause Review, 2022 In recent decades many potential serum biomarkers have been assessed in the diagnosis of ovarian cancer. Except cancer antigen 125 (CA125) and human epididymis protein 4 (HE4), none of them have been applied to everyday clinical practice.
Łukasz Janas, Ewa Kalinka, Marek Nowak
doaj +1 more source
Biochemistry and Biophysics Reports, 2018 The magnetic particles have a significant influence on the immunoassay detection and cancer therapy. Herein, the chemiluminescence immunoassay combined with the magnetic particles (MPCLIA) was presented for the clinical determination and analysis of ...
Xiaoling Fu +6 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2019 Upregulation of human epididymis protein 4 (HE4) is often observed in different types of cancers, including gastric cancer (GC), but the association of elevated HE4 level with radiation resistance in GC remains unclear.
Chunwei Peng +5 more
doaj +1 more source
HE4 in the differential diagnosis of ovarian masses [PDF]
, 2015 Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela +5 more
core +1 more source
HE4 Predicts Progressive Fibrosis and Cardiovascular Events in Patients With Dilated Cardiomyopathy
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Cardiac fibrosis plays a crucial role in the pathogenesis of dilated cardiomyopathy (DCM). HE4 (human epididymis protein 4) is a secretory protein expressed in activated fibroblasts that exacerbates tissue fibrosis.
Masahiro Yamamoto +18 more
doaj +1 more source
HE4 Transcription- and Splice Variants-Specific Expression in Endometrial Cancer and Correlation with Patient Survival [PDF]
, 2013 We investigated the HE4 variant-specific expression patterns in various normal tissues as well as in normal and malignant endometrial tissues. The relationships between mRNA variants and age, body weight, or survival are analyzed. ICAT-labeled normal and
Attewell, John +9 more
core +2 more sources