The Role of Whey Acidic Protein Four-Disulfide-Core Proteins in Respiratory Health and Disease [PDF]
, 2016 Members of the whey acidic protein (WAP) or WAP four-disulfide-core (WFDC) family of proteins are a relatively under-explored family of low molecular weight proteins. The two most prominent WFDC proteins, secretory leukocyte protease inhibitor (SLPI) and
Doherty, Declan F. +4 more
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Engineering Proceedings, 2023 Noble metal nanostructured substrates enhance photoluminescence emitted from molecules immobilized onto their surface, allowing for the development of highly sensitive immunoassays employing fluorescent labels.
Georgia Geka +11 more
doaj +1 more source
Roles of human epididymis protein 4, carbohydrate antigen 125, inhibin B and anti-Mullerian hormone in the differential diagnosis and follow-up of ovarian granulosa cell tumors [PDF]
, 2017 Objective. Evaluation of circulating tumor markers in ovarian cancer is crucial for optimal patient care. The goal of this study was to verify the most accurate circulating tumor markers for the diagnosis and follow-up of adult-type granulosa cell tumors
Alfthan, Henrik +10 more
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Open Medicine, 2016 To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer.
Zheng Li-e, Qu Jun-ying, He Fei
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Evaluation of tumor marker HE4 assay on the Elecsys 2010 analyzer
Journal of Health Sciences, 2014 Introduction: Whey-acidic protein human epididymis protein 4 (HE4) is a new promising biomarker for epithelial ovarian cancer. The measured HE4 values may depend on the testing procedure used.
Jozo Ćorić +3 more
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A Review on Biomarker-Enhanced Machine Learning for Early Diagnosis and Outcome Prediction in Ovarian Cancer Management. [PDF]
Cancer MedABSTRACT Background Ovarian cancer (OC) remains the most lethal gynecological malignancy, largely due to its late‐stage diagnosis and nonspecific early symptoms. Advances in biomarker identification and machine learning offer promising avenues for improving early detection and prognosis.
Hormaty S +5 more
europepmc +2 more sources
Improved early detection of ovarian cancer using longitudinal multimarker models [PDF]
, 2019 © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Blyuss, Oleg +10 more
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Highly elevated human epididymis protein 4 (HE4) following endometrioma rupture: a case report
Journal of Obstetrics and Gynaecology, 2018 Several serum tumour markers have been widely used for years to detect ovarian malignancies. However, to date, the best tumour marker to differentiate between benign and malignant ovarian masses/cy...
Yavuz Emre, Şükür +4 more
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Advances of Human Epididymis Protein 4 in Lung Cancer
Chinese Journal of Lung Cancer, 2015 Human epididymis 4 (HE4) belongs to whey acidic 4-disulfide center protein family. It has the characteristics of inhibiting trypsin and high expression in the serum or malignant pleural effusion of patients with lung cancer.
Qing MA, Qian WANG, Diansheng ZHONG
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Evaluation of Serum Human Epididymis Secretory Protein 4 (HE4) in Benign Endometrial Disease and Endometrial Cancer [PDF]
QJM: An International Journal of Medicine, 2020 Abstract Objective The incidence of endometrial cancer is constantly growing. More aggressive types of endometrial cancer as well as the incidence in younger women are being observed. More than 80% of cases are diagnosed in early stages due to early symptoms like abnormal bleeding. Aim of our study to
F M Abukra +3 more
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