Results 51 to 60 of about 4,477 (231)

Beyond the Biomarker: Understanding the Diverse Roles of Human Epididymis Protein 4 in the Pathogenesis of Epithelial Ovarian Cancer

open access: yesFrontiers in Oncology, 2018
Human epididymis protein 4 (HE4) is an important clinical biomarker used for the detection of epithelial ovarian cancer (EOC). While much is known about the predictive power of HE4 clinically, less has been reported regarding its molecular role in the ...
Nicole E. James   +3 more
doaj   +1 more source

Serum Human Epididymis Protein 4 is a Potential Biomarker for Early Chronic Kidney Disease in an Obese Population

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2021
Shubo Tan, Yongmao Zeng, Shiliang Kuang, Jianjun Li Department of Urology, Second Affiliated Hospital of the University of South China, Hengyang City, 421000, People’s Republic of ChinaCorrespondence: Jianjun LiDepartment of Urology, Second ...
Tan S, Zeng Y, Kuang S, Li J
doaj  

Dual-label time-resolved fluoroimmunoassay for simultaneous measurement of human epidermal growth factor receptor 2 and human epididymis protein 4 in serum

open access: yesJournal of Analytical Science and Technology, 2020
In this study, a novel dual-label time-resolved fluoroimmunoassay (TRFIA) is described for simultaneous quantification of human epidermal growth factor receptor 2 (HER-2) and human epididymis protein 4 (HE4) in serum to screen gynecologic cancers.
Yi Zhang   +9 more
doaj   +1 more source

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma [PDF]

open access: yes, 2016
Serum protein fingerprints associated with MGUS and MM and their changes in MM after autologous stem cell transplantation (MM-ASCT, day 100) remain unexplored.
Fillerová, Regina   +9 more
core   +1 more source

HE4 (WFDC2) Promotes Tumor Growth in Endometrial Cancer Cell Lines [PDF]

open access: yes, 2013
HE4, also known as WFDC2, is a useful biomarker for ovarian cancer when either used alone or in combination with CA125. HE4 is also overexpressed in endometrial cancer (EC), but its function in cancer cells is not clear. In this study, we investigate the
Broaddus, Russell   +9 more
core   +2 more sources

Serum Human Epididymis Protein 4 (HE4) in the Differential Diagnosis of Peritoneal Tuberculosis: A Report of Two Cases. [PDF]

open access: yesBalkan Med J, 2014
Dear Editor, Peritoneal tuberculosis mimics ovarian cancer due to clinical, radiological and laboratory similarities (1). Patients with peritoneal tuberculosis usually have weight loss, abdominal pain and gastrointestinal symptoms similar to ovarian cancer.
Kabaca C   +3 more
europepmc   +5 more sources

Evaluation of human epididymal secretory protein 4 expression according to the molecular subtypes (luminal A, luminal B, human epidermal growth factor receptor 2-positive, triple-negative) of breast cancer

open access: yesIndian Journal of Pathology and Microbiology, 2018
Background/Aims: Human epididymal secretory protein 4 (HE4) is originally described as an epididymis-specific protein but more recently suggested to be a putative serum tumor marker for some tumors, including breast carcinomas. In this study, we aimed to
Gamze Akoz   +4 more
doaj   +1 more source

Co-expression of Lewis y antigen with human epididymis protein 4 in ovarian epithelial carcinoma. [PDF]

open access: yesPLoS ONE, 2013
OBJECTIVE:The main aims of this study were to explore the molecular structural relationship between Human epididymis protein 4 (HE4) and Lewis y antigen by determining their expression patterns and clinical significance in ovarian epithelial carcinoma ...
Huiyu Zhuang   +5 more
doaj   +1 more source

HE4 tumor marker concentration in neoplastic peritoneal effusion and in peritoneal fluid associated with benign gynecological diseases [PDF]

open access: yes, 2014
BACKGROUND: The aim of our study was to evaluate the behaviour of the human epididymis protein 4 (HE4) in the peritoneal fluid encountered in various female genital diseases.
Agnieszka Sompolska-Rzechuła   +5 more
core   +1 more source

Serum HE4 and CA125 combined to predict and monitor recurrence of type II endometrial carcinoma

open access: yesScientific Reports, 2021
There is no recognized serum biomarker to predict the recurrence of endometrial carcinoma (EC). We aimed to explore serum human epididymis protein 4 (HE4) and cancer antigen 125 (CA125) as the biomarkers to predict and monitor recurrence of type II EC ...
Quan Quan   +5 more
doaj   +1 more source

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