Results 81 to 90 of about 4,477 (231)

Ovarian cancer: can proteomics give new insights for therapy and diagnosis? [PDF]

, 2013
The study of the ovarian proteomic profile represents a new frontier in ovarian cancer research, since this approach is able to enlighten the wide variety of post-translational events (such as glycosylation and phosphorylation). Due to the possibility of
Casa L. D., CORTESI, LAURA, DE MATTEIS, Elisabetta, FEDERICO, Massimo, IANNONE, Anna, ROSSI, Elena, TOSS, ANGELA   +6 more
core   +2 more sources

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

International Journal of Cancer, Volume 158, Issue 6, Page 1755-1768, 15 March 2026.
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam, Xiaojun Zhang, Riajul Wahab, Md Mahedi Hasan, Shivaniben Dhadhal, Bowon Kang, Md Mynul Hassan, Mazharul Karim, Jeong Uk Choi, Muhit Rana, Jian‐Ying Zhang, Sourav Roy, Youngro Byun, In‐San Kim, Jae Yun Song, Eugene P. Toy, Sireesha Y. Reddy, Farzana Alam, Taslim A. Al‐Hilal   +18 more
wiley   +1 more source

A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis [PDF]

, 2016
Citation: Zhao, Z., Yang, Y., Zeng, Y., & He, M. (2016). A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis. Lab on a Chip, 16(3), 489-496. doi:10.1039/c5lc01117eTumor-derived circulating exosomes,
He, Mei, Yang, Y., Zeng, Y., Zhao, Z.
core   +2 more sources

A Cost Consequence Analysis of Seven Diagnostic Strategies for Ovarian Cancer: A Model‐Based Economic Evaluation

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 680-689, March 2026.
ABSTRACT Objective To assess the costs and consequences of seven diagnostic strategies for ovarian cancer in pre‐ and post‐menopausal women with symptoms in secondary care. Design Economic evaluation alongside a prospective single‐arm diagnostic accuracy study.
Samuel J. Perry, Donal Griffin, Eleanor V. Williams, Tracy E. Roberts, Fong Lien Kwong, Sarah Williams, Jon Deeks, Katie Scandrett, Ridhi Agarwal, Sudha S. Sundar, Mark Monahan   +10 more
wiley   +1 more source

HE4 – not only an ovarian cancer biomarker – a brief review [PDF]

, 2019
Human epididymis protein 4 (HE4) was firstly identified in epididymal epithelial cells and described as a protease inhibitor playing a role in spermatogenesis. Regarding numerous studies proving its diverse potential as a prognostic and predictive factor
Badowska-Kozakiewicz, Anna M., Budzik, Michał P., Deptała, Andrzej, Maksimiuk, Marta   +3 more
core   +3 more sources

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Primary Mesonephric‐Like Adenocarcinoma of the Ovary: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT We report a 67‐year‐old female diagnosed with ovarian mesonephric‐like adenocarcinoma (MLA) and treated with a comprehensive regimen. This case emphasizes the urgent need for standardized diagnostic criteria and evidence‐based treatment protocols for ovarian MLA, aiming to improve clinicians' understanding and support clinical decision‐making.
Na Zuo, Li Peng, Di Wu, Gang Lv, Lu Yang
wiley   +1 more source

Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset [PDF]

, 2015
Early detection of ovarian cancer through screening may have impact on mortality from the disease. Approaches based on CA125 cut-off have not been effective.
Blyuss, O, Fourkala, EO, Gentry-Maharaj, A, Jacobs, I, Menon, U, Ryan, A, Timms, JF, Zaikin, A   +7 more
core   +3 more sources

HE4 tumor marker as a predictive factor for lymphatic metastasis in endometrial cancer [PDF]

, 2020
Endometrial cancer is the most common genital cancer in high-resource countries. Treatment is essentially surgical, but the role of lymphadenectomy in the treatment of low-stage and low-grade tumors has not been defined.
Baquedano Mainar, L., Benito Vielba, M., Coronado Martín, P.J., Cuesta Guardiola, T., De Bonrostro Torralba, C., Espiau Romera, A.   +5 more
core   +1 more source

Borderline ovarian tumours

The Obstetrician &Gynaecologist, Volume 27, Issue 4, Page 321-331, October 2025.
Key content Borderline ovarian tumours (BOTs) are a diverse and heterogeneous set of diseases, which are encountered by all obstetricians and gynaecologists. They occur on average around 10 years earlier than malignant ovarian cancers and are associated with a significantly better prognosis. Preoperative diagnosis of BOTs is challenging as radiological
Holly Baker‐Rand, James Bolton, Robert D. Morgan, Richard Edmondson   +3 more
wiley   +1 more source