Results 41 to 50 of about 78,351 (172)

Human-Gut-DNA Virome Variations across Geography, Ethnicity, and Urbanization [PDF]

Cell Host & Microbe, 2020
The human-gut-DNA virome is highly diverse and individual specific, but little is known of its variation at a population level. Here, we report the fecal DNA virome of 930 healthy adult subjects from two regions in China (Hong Kong and Yunnan) spanning six ethnicities (Han, Zang, Miao, Bai, Dai, and Hani), and including urban and rural residents for ...
Tao, Zuo, Yang, Sun, Yating, Wan, Yun Kit, Yeoh, Fen, Zhang, Chun Pan, Cheung, Nan, Chen, Juan, Luo, Wen, Wang, Joseph J Y, Sung, Paul K S, Chan, Kunhua, Wang, Francis K L, Chan, Yinglei, Miao, Siew C, Ng   +14 more
openaire   +2 more sources

Alterations in the Composition of Intestinal DNA Virome in Patients With COVID-19

Frontiers in Cellular and Infection Microbiology, 2021
Patients with Coronavirus Disease 2019 (COVID-19), due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection mainly present with respiratory issues and related symptoms, in addition to significantly affected digestive system ...
Zhen-Hua Lu, Hao-Wei Zhou, Hao-Wei Zhou, Wei-Kang Wu, Wei-Kang Wu, Ting Fu, Min Yan, Zhen He, Shi-Wei Sun, Shi-Wei Sun, Zhao-Hua Ji, Zhong-jun Shao   +11 more
doaj   +1 more source

The human gut microbiota and virome: Potential therapeutic implications [PDF]

Digestive and Liver Disease, 2015
Human gut microbiota is a complex ecosystem with several functions integrated in the host organism (metabolic, immune, nutrients absorption, etc.). Human microbiota is composed by bacteria, yeasts, fungi and, last but not least, viruses, whose composition has not been completely described. According to previous evidence on pathogenic viruses, the human
Scarpellini, Emidio, Ianiro, Gianluca, Attili, Fabia, Bassanelli, Chiara, De Santis, Adriano, Gasbarrini, Antonio   +5 more
openaire   +3 more sources

Early life dynamics of the human gut virome and bacterial microbiome in infants [PDF]

Nature Medicine, 2015
The early years of life are important for immune development and influence health in adulthood. Although it has been established that the gut bacterial microbiome is rapidly acquired after birth, less is known about the viral microbiome (or 'virome'), consisting of bacteriophages and eukaryotic RNA and DNA viruses, during the first years of life. Here,
E. Lim, Yanjiao Zhou, Guoyan Zhao, Irma K. Bauer, L. Droit, I. Ndao, Barbara B. Warner, Phillip I. Tarr, David Wang, Lori R. Holtz   +9 more
semanticscholar   +3 more sources

Virome Sequencing of the Human Intestinal Mucosal–Luminal Interface

Frontiers in Cellular and Infection Microbiology, 2020
While the human gut virome has been increasingly explored in recent years, nearly all studies have been limited to fecal sampling. The mucosal–luminal interface has been established as a viable sample type for profiling the microbial biogeography of the ...
Austin Yan, James Butcher, David Mack, David Mack, Alain Stintzi   +4 more
doaj   +1 more source

Dynamic changes occur in the DNA gut virome of female cynomolgus macaques during aging

MicrobiologyOpen, 2021
Aging is a critical factor affecting physical health and disease in mammals. Emerging evidence indicates that aging may affect the gut bacteriome in cynomolgus macaques, but little is known about whether or how the gut virome changes with age.
Xunmin Tan, Tingjia Chai, Jiajia Duan, Jing Wu, Hanping Zhang, Yifan Li, Yu Huang, Xi Hu, Peng Zheng, Jinlin Song, Ping Ji, Xin Jin, Hongmei Zhang, Peng Xie   +13 more
doaj   +1 more source

DOP53 Community types of the human gut virome are associated with endoscopic outcome in UC patients

Journal of Crohn's & Colitis, 2023
Inflammatory bowel diseases (IBD) are a group of chronic inflammatory diseases of the gut. The pathophysiology is unknown; however, it is thought to result from an inappropriate immune reaction to the commensal gut microbiota. Community-typing is a
D. Jansen, G. Falony, S. Vieira-Silva, C. Simsek, T. Marcelis, K. Machiels, C. Caenepeel, J. Raes, V. Séverine, J. Matthijnssens   +9 more
semanticscholar   +1 more source

The gut virome: the ‘missing link’ between gut bacteria and host immunity?

Therapeutic Advances in Gastroenterology, 2019
The human gut virome includes a diverse collection of viruses that infect our own cells as well as other commensal organisms, directly impacting on our well-being. Despite its predominance, the virome remains one of the least understood components of the
Indrani Mukhopadhya, Jonathan P. Segal, Simon R. Carding, Ailsa L. Hart, Georgina L. Hold   +4 more
doaj   +1 more source

Community types of the human gut virome are associated with endoscopic outcome in ulcerative colitis

medRxiv, 2022
Objective IBD patients have an altered gut virome composition; however, the relationship to disease is unknown. Our aim is to investigate the existence of viral community types and assess the impact of therapeutic outcome (and other covariates) on the ...
G. Falony, S. Vieira-Silva, C. Simsek, T. Marcelis, Clara, Caenepeel, K. Machiels, J. Raes, Séverine Vermeire, J. Matthijnssens   +9 more
semanticscholar   +1 more source

The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications

Viruses, 2022
The human body is colonized by a wide range of microorganisms. The field of viromics has expanded since the first reports on the detection of viruses via metagenomic sequencing in 2002. With the continued development of reference materials and databases,
Geng-Hao Bai, Sheng-Chieh Lin, Yi-Hsiang Hsu, Shih-Yen Chen   +3 more
doaj   +1 more source