Results 61 to 70 of about 27,320,927 (309)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A systemic risk assessment methodological framework for the global polycrisis

Nature Communications
Human societies and ecological systems face increasingly severe risks, stemming from crossing planetary boundaries, worsening inequality, rising geo-political tensions, and new technologies.
Ajay Gambhir, Michael J. Albert, Sylvanus S. P. Doe, Jonathan F. Donges, Nadim Farajalla, Leandro L. Giatti, Haripriya Gundimeda, Sarah Hendel-Blackford, Thomas Homer-Dixon, Daniel Hoyer, Sumaya Adan, David Jacome-Polit, Luke Kemp, David Korowicz, Zora Kovacic, Jan Kwakkel, Laurie Laybourn, Robert Lempert, Ayan Mahamoud, Tom H. Oliver, Ivana E. Pavkova, Joseph Ponnoly, Vishwas Satgar, Megan Shipman, Jana Sillmann, Nick Silver, Samuel Stevenson, Ruth Richardson   +27 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health risk assessment of volatile organic compounds in urban areas

, 2017
The atmosphere is the first medium containing hazardous compounds entering the living environment. Metropolitan areas contain many industrial complex areas with high emissions of volatile organic compounds (VOCs), and consequently also large-scale ...
신동천, 임영욱, 이용진
core   +1 more source

Systematic review and economic modelling of the relative clinical benefit and cost-effectiveness of laparoscopic surgery and robotic surgery for removal of the prostate in men with localised prostate cancer [PDF]

, 2012
PMID: 23127367 [PubMed - indexed for MEDLINE] Free full text Funding for this study was provided by the Health Technology Assessment programme of the National Institute for Health Research.Peer ...
Royle, J., C Robertson, Pickard, R., C Ramsay, Close, A, Jia, X., Fraser, C., Armstrong, N, Royle, J, Rushton, S P, Robertson, C., Ramsay, C, D Jenkinson, Gurung, T, Lam, T B, Mowatt, G, Fraser, C, Neal, D. E., Rushton, S. P., Armstrong, N., Eden, C. G., MC Robinson, Jenkinson, D, Robinson, M. C., CG Eden, Vale, L, Sharma, P., MDF Shirley, DA Barocas, Lam, T. B., Sharma, P, J Royle, Neal, D E, L Vale, Close, A., Barocas, D A, Robinson, M C, A Close, Robertson, C, TB Lam, DE Neal, Ramsay, C. R. (Craig R.), Gurung, T. (Tara), Mowatt, G., C Fraser, Shirley, M D F, SP Rushton, N Armstrong, Pickard, R, Eden, C G, Barocas, D. A., P Sharma, Vale, L. (Luke), Jenkinson, D., T Gurung, R Pickard, Soomro, N., G Mowatt, Shirley, M. D. F., Jia, X, Soomro, N, N Soomro, X Jia   +62 more
core   +1 more source

Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae

mBio, 2020
Transporters belonging to the chromosomally encoded resistance-nodulation-division (RND) superfamily mediate multidrug resistance in Gram-negative bacteria.
Luchao Lv, Miao Wan, Chengzhen Wang, Xun Gao, Qiwen Yang, Sally R. Partridge, Yang Wang, Zhiyong Zong, Yohei Doi, Jianzhong Shen, Peiyao Jia, Qianhua Song, Qianhui Zhang, Jun Yang, Xianhui Huang, Minggui Wang, Jian-Hua Liu   +16 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Genomic and transcriptomic analyses reveal distinct biological functions for cold shock proteins (VpaCspA and VpaCspD) in Vibrio parahaemolyticus CHN25 during low-temperature survival

BMC Genomics, 2017
Background Vibrio parahaemolyticus causes serious seafood-borne gastroenteritis and death in humans. Raw seafood is often subjected to post-harvest processing and low-temperature storage.
Chunhua Zhu, Boyi Sun, Taigang Liu, Huajun Zheng, Wenyi Gu, Wei He, Fengjiao Sun, Yaping Wang, Meicheng Yang, Weicheng Bei, Xu Peng, Qunxin She, Lu Xie, Lanming Chen   +13 more
doaj   +1 more source