Results 81 to 90 of about 27,320,927 (309)

Health Risk Assessment of PET Bottles in GCC

, 2013
Bottle water is getting very popular all through the world; especially in the gulf countries as the main source of drinking water. However, concerns over leaching of toxic chemicals are increasing. In this study, a health risk assessment was conducted
Mortula, Maruf
core  

Long-term exposure to particulate matter, NO2 and the oxidative potential of particulates and diabetes prevalence in a large national health survey

Environment International, 2017
Background: The evidence from observational epidemiological studies of a link between long-term air pollution exposure and diabetes prevalence and incidence is currently mixed. Some studies found the strongest associations of diabetes with fine particles,
Maciej Strak, Nicole Janssen, Rob Beelen, Oliver Schmitz, Ilonca Vaartjes, Derek Karssenberg, Carolien van den Brink, Michiel L. Bots, Martin Dijst, Bert Brunekreef, Gerard Hoek   +10 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A review of occupational health and safety risk assessment approaches based on multi-criteria decision-making methods and their fuzzy versions

, 2018
Occupational health and safety (OHS) is a multidisciplinary activity working under the tasks of protection of workers and worksites. Risk assessment, as a compulsory process in implementation of OHS, stands out as evaluating the risks arising from the ...
Muhammet Gul, Gul, Muhammet
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A new fuzzy-based approach for environmental risk assessment

, 2019
Due to new regulations, laws and increasing demand from consumers, companies begin to enhance their environmental management practices. Hence, environmental risk assessment became one of the critical success factors for companies in order to be ...
Oturakci, Murat
core   +1 more source

Risks for public health related to the presence of chlorate in food

EFSA Journal, 2015
Following a request from the European Commission, the risks to human health related to the presence of chlorate in food were assessed by the EFSA Panel on Contaminants in the Food Chain (CONTAM Panel).
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Long-term exposure to outdoor artificial light-at-night and its associations with natural-cause and cause-specific mortality: a register-based cohort study in the Netherlands

Environment International
Background: Outdoor artificial light-at-night (ALAN) is increasingly recognized as a potential environmental health risk. Epidemiological evidence mainly comes from incidence studies, whereas cause-specific mortality, reflecting disease occurrence and ...
Tian Tian, Roel Vermeulen, Marco Helbich
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source