CURRENT CONCEPT OF HUMAN HERPESVIRUS TYPE 6 INFECTION [PDF]
Human herpes virus type 6 infection is widely distributed. It is extensively studied recent years due to the imperfection of diagnostics, as well as participa- tion in the formation of chronic somatic pathology.
E. V. Melehina +4 more
doaj +2 more sources
Herpes simplex virus interferes with amyloid precursor protein processing. [PDF]
Background The early events underlying Alzheimer's disease (AD) remain uncertain, although environmental factors may be involved. Work in this laboratory has shown that the combination of herpes simplex virus type 1 (HSV1) in brain and carriage of the ...
Shipley, Suzanne J. +3 more
core +6 more sources
Multiple Sclerosis and Viruses: « Liaisons Dangereuses ». [PDF]
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Plavina S +11 more
europepmc +2 more sources
Herpes simplex virus triggers and then disarms a host antiviral response [PDF]
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R +5 more
core +1 more source
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu +16 more
core +1 more source
Herpes simplex virus type 2: epidemiology and management options in developing countries [PDF]
Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical ...
Geretti, AM +7 more
core +1 more source
Background: Febrile neutropenia is a common complication in adult patients undergoing chemotherapy for hematological malignancies. A potential causative agent is identified in approximately one third of the fever episodes.
Igge Gustafsson +4 more
doaj +1 more source
Co-Delivery of Varicella Zoster Virus gE and gI Dual-Antigen mRNA Vaccine With CpG-ODN Elicits Robust Immunity. [PDF]
The gE+gI Lmix+CpG‐ODN 1018 vaccine was formulated by combining gE and gI mRNA/LNPs with the TLR9 agonist adjuvant CpG‐ODN 1018. This formulation induces robust humoral and cellular immunity while maintaining a favorable safety profile and physiological stability in mice.
Cui L +15 more
europepmc +2 more sources
The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow
Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible ...
M. Yu. Lysenkova +11 more
doaj +1 more source
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Rixon Frazer J. +23 more
core +1 more source

