Results 21 to 30 of about 8,717,811 (163)

Human Herpesviruses-encoded dUTPases: A Family of Proteins that Modulate Dendritic Cell Function and Innate Immunity

Frontiers in Microbiology, 2014
We have previously shown that Epstein-Barr virus (EBV)-encoded dUTPase can modulate innate immune responses through the activation of TLR2 and NF-kappaB signaling. However, whether this novel immune function of the dUTPase is specific for EBV or a common
Maria Eugenia eAriza, Ronald eGlaser, Marshall Vance Williams   +2 more
doaj   +1 more source

Infectious agents and Alzheimer's disease

Journal of Integrative Neuroscience, 2022
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Individuals affected by the disease gradually lose their capacity for abstract thinking, understanding, communication and memory.
Thomas Piekut, Mikołaj Hurła, Natalia Banaszek, Paulina Szejn, Jolanta Dorszewska, Wojciech Kozubski, Michał Prendecki   +6 more
doaj   +1 more source

Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]

, 2007
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre, Van de Perre, Philippe, Sanon, Anselme, Segondy, Michel, Weiss, Helen A, Andonaba, Jean-Baptiste, Vallo, Roselyne, ANRS 1285 Study Group, Sawadogo, Adrien, Nagot, Nicolas, Foulongne, Vincent, Vergne, Laurence, Mayaud, Philippe, Ouédraogo, Abdoulaye, Defer, Marie-Christine, Djagbaré, Didier, Konaté, Issouf   +16 more
core   +1 more source

Seroepidemiological study of herpes simplex virus types 1 and 2 in Brazil, Estonia, India, Morocco, and Sri Lanka [PDF]

, 2003
Background: The association between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) and the development of HSV vaccines have increased interest in the study of HSV epidemiology.Objectives: To estimate the age and sex specific ...
Rbai, M, Robinson, NJ, de Oliveira, S Artimos, Gopal, R, Nygard-Kibur, M, Alami, K, Cowan, FM, Uuskula, A, Brown, DW, Mayaud, P, Sridharan, G, El Aouad, R, Ramalingam, S, de Oliveira, SA, Sunil-Chandra, NP, Faillace, T, French, RS   +16 more
core   +1 more source

Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]

, 2015
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA, Breuer, J, Gompels, UA, Tweedy, J, Depledge, D, Donaldson, CD   +5 more
core   +1 more source

The role of human betaherpesviruses 6A and 6B in the pathogenesis of multiple sclerosis: a modern view of the problem

Журнал инфектологии
The role of human herpes virus 6A and human herpes virus 6B in the pathogenesis of multiple sclerosis remains a matter of debate, largely due to the multifactorial nature of the neurological disease.
N. A. Suslov, A. E. Hrulev, E. N. Filatova, N. Zajceva, I. N. Vaneev, O. V. Utkin   +5 more
doaj   +1 more source

Latency, Integration, and Reactivation of Human Herpesvirus-6

Viruses, 2017
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
doaj   +1 more source

Analyses of germline, chromosomally integrated human herpesvirus 6A and B genomes indicate emergent infection and new inflammatory mediators.

, 2014
Human herpesvirus-6A (HHV-6A) is rarer than HHV-6B in many infant populations. However, they are similarly prevalent as germline, chromosomally integrated genomes (ciHHV-6A/B).
Spyrou, MA, Hubacek, P, Lassner, D, Kuhl, U, Gompels, UA, Tweedy, J   +5 more
core   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Mascolo, Andrea, Arbusow, Viktor, Theil, Diethilde, Brandt, Thomas, Strupp, Michael   +4 more
core   +1 more source

The Telomeric Repeats of HHV-6A Do Not Determine the Chromosome into Which the Virus Is Integrated

, 2023
Human herpes virus 6A (HHV-6A) is able to integrate into the telomeric and subtelomeric regions of human chromosomes representing chromosomally integrated HHV-6A (ciHHV-6A). The integration starts from the right direct repeat (DRR) region.
Olga V. Goleva, Anna L. Mukomolova, Natalia S. Tian, Andrey V. Krylov, Lavrentii G. Danilov, Roman S. Kalinin, Aleksey S. Komissarov, Victoria V. Tsay, Aleksey V. Kusakin, Yuri A. Eismont, Alexei B. Chukhlovin, Oleg S. Glotov   +11 more
core   +1 more source