Animal herpesviruses and their zoonotic potential for cross-species infection
Herpesviruses of humans and animals cause severe diseases that influence not only the health and epidemiological status but are also economically important in the context of food production.
Grzegorz Woźniakowski +1 more
doaj +3 more sources
Human herpes virus type 6 (Orthoherpesviridae: Roseolovirus): features of epidemiology and diagnosis
Human herpes virus 6A and human herpes virus 6B (HHV-6A and HHV-6B) are ubiquitous viruses. The spectrum of clinical manifestations of HHV-6A/B infections is quite wide.
Inara S. Saydullayeva +3 more
doaj +1 more source
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes [PDF]
Components of promyelocytic leukaemia (PML) nuclear bodies (ND10) are recruited to sites associated with herpes simplex virus type 1 (HSV-1) genomes soon after they enter the nucleus. This cellular response is linked to intrinsic antiviral resistance and
Delphine Cuchet-Lourenço +24 more
core +1 more source
Control of herpes simplex virus type 1 latency in human trigeminal ganglia [PDF]
Herpes simplex virus type 1 (HSV-1) is a double-stranded DNA virus that infects humans and, after a primary lytic infection, establishes lifelong latency in the sensory neurons of the trigeminal ganglia (TG).
Held, Kathrin
core +1 more source
An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Heather M. Coleman +13 more
core +1 more source
Could autophagy dysregulation link neurotropic viruses to Alzheimer’s disease?
Neurotropic herpesviruses have been associated with the onset and progression of Alzheimer’s disease, a common form of dementia that afflicts a large percentage of elderly individuals.
Maria Anele Romeo +2 more
doaj +1 more source
Seroprevalence, predictors and estimated incidence of maternal and neonatal Herpes Simplex Virus Type 2 infection in semi-urban women in Kilifi, Kenya [PDF]
Background: Herpes Simplex Virus type 2 (HSV-2) has public health importance as a leading cause of genital ulcers, a co-factor in HIV-1 acquisition and transmission and as a cause of neonatal herpes infections.
Awuondo Ken +26 more
core +2 more sources
A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Synergistic interactions between human herpesvirus 6A (HHV‐6A) and Epstein–Barr virus (EBV) are hypothesized in the etiopathogenesis of multiple sclerosis (MS). This study investigated if HHV‐6A and EBV seroreactivities interact regarding the risk of developing MS.
Viktor Grut +11 more
openaire +3 more sources
Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source

