Results 91 to 100 of about 130,487 (185)

Complete genome sequences of elephant endotheliotropic herpesviruses 1A and 1B determined directly from fatal cases [PDF]

, 2013
A highly lethal hemorrhagic disease associated with infection by elephant endotheliotropic herpesvirus (EEHV) poses a severe threat to Asian elephant husbandry.
Alcendor DJ, Anonymous, Chee MS, Das S, Davison AJ, Davison AJ, Davison AJ, Denk D, Ehlers B, Ewing B, Fickel J, Garner MM, Hardman K, Hayward GS, Honess RW, Jacobson ER, Lesniewski M, McCully RM, McGeoch DJ, Milne I, Milne RSB, Neote K, Ossent P, Pellett PE, Reid CE, Richman LK, Rixon FJ, Ryan SJ, Schaftenaar W, Schmitt DL, Staden R, Stanton JJ, Stern-Ginossar N   +32 more
core   +1 more source

Seropositivity against rubella virus envelope protein 1, but not 2, is associated with an increased risk of multiple sclerosis

Clinical &Translational Immunology, Volume 15, Issue 4, 2026.
In samples collected before the onset of multiple sclerosis (MS), we show that seropositivity against rubella virus (RV) envelope protein 1 (E1) was associated with increased risk of developing MS. Furthermore, at group level, cases had higher seroreactivity against RV E1 compared to matched controls before a significant increase in neurofilament light
Jens Ingvarsson, Viktor Grut, Martin Biström, Linn Persson Berg, Julia Butt, Birgitta Michels, Pernilla Stridh, Tomas Olsson, Lars Alfredsson, Ingrid Kockum, Tim Waterboer, Staffan Nilsson, Peter Sundström   +12 more
wiley   +1 more source

A viral APOBEC3 antagonist distinguishes HHV-6A from HHV-6B

Nature Communications
Human herpesviruses exhibit diverse pathogenic outcomes and the molecular reasons are not fully understood. Human herpesvirus 6B (HHV-6B) causes exanthema subitum and encephalitis, whereas the closely related HHV-6A is typically asymptomatic.
Jun Arii, Salma Aktar, Jing Rin Huang, Mansaku Hirai, Yoshiki Kawamura, Hiroki Miura, Bochao Wang, Satoshi Nagamata, Mitsuhiro Nishimura, Tetsushi Yoshikawa, Reuben S. Harris, Yasuko Mori   +11 more
doaj   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein [PDF]

, 2009
The nucleocapsid (N) protein of severe acute respiratory syndrome (SARS) coronavirus plays important roles in both viral replication and modulation of host cell processes.
Amstutz, C. Anders Olson, Cardinale, Cardinale, Carlson, Carter, Chakrabarti, Chang, Chen, Elaine Wong, Enjuanes, Hongyu Deng, Hosse, Hsiang-I. Liao, Ja, Kawe, Koide, Lipovsek, Liu, Luo, Maynard, Milligan, Nizak, Olson, Olson, Rajpal, Ralph S. Baric, Ren Sun, Richard W. Roberts, Roberts, Roberts, Rota, Saikatendu, Satija, Seungmin Hwang, Stocks, Surjit, Vascotto, Visintin, Yount, Yu   +40 more
core   +4 more sources

Combination of Vaccine With IL‐12‐Armed Oncolytic Virus SKV‐012 Synergistically Potentiates Immune Responses in HPV‐Associated Malignancies

MedComm, Volume 7, Issue 4, April 2026.
A synergistic immunotherapeutic platform based on the intratumoral delivery of oncolytic virus and intramuscular vaccination activates both local and systemic antitumor immunity. This synergistic approach expands the universality and therapeutic efficacy of vaccines in HPV‐associated malignancies.
Nian Yang, Long Xu, Meijun Zheng, Huaqing Lu, Yongdong Chen, Zhixiong Zhu, Wanqin Zeng, Zeng Wang, Hexian Li, Jia Li, Zheng Jiang, Pingfu Zeng, Guoqing Wang, Hai Xie, Zongliang Zhang, Hui Yang, Aiping Tong   +16 more
wiley   +1 more source

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid, Couck, Liesbeth, Favoreel, Herman, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +7 more
core   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, Volume 293, Issue 8, Page 2314-2340, April 2026.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]

, 2013
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund, Badens, Baker, Berk, Berube, Blanchette, Carolin Bürck, Chatterjee, Cheng, Chinnadurai, Cuchet-Lourenco, Dallaire, Dellaire, Dobner, Drane, Everett, Flint, Frisch, Gibbons, Glass, Goldberg, Goldberg, Gostissa, Graham, Groitl, Gunther, Hancock, Harlow, Hassan, Hollenbach, Ishov, Ishov, Jin, Kahyo, Kindsmuller, Kindsmuller, Kindsmüller, Ko, Komatsu, Kosulin, Lewis, Lewis, Li, Lukashchuk, Lukashchuk, Mandy Glass, Marton, Matsumoto, Maul, McFarlane, Michaelson, Mitsudomi, Mund, Nevels, Nevins, Nevins, Niforou, Okuwaki, Orazio, Parks, Pelka, Peter Groitl, Peter Wimmer, Placek, Querido, Roger D. Everett, Ross, Rubenwolf, Sabrina Schreiner, Salomoni, Sarah Kinkley, Sarnow, Schreiner, Schreiner, Schreiner, Shenk, Si, Song, Stracker, Takahashi, Tang, Thomas Dobner, Torii, Täuber, Täuber, Ullman, White, Williams, Wilson, Wong, Wong, Xu, Xue   +92 more
core   +1 more source

Drug‐induced hypersensitivity syndrome followed by exacerbation of Crohn's disease

Pediatric Investigation, EarlyView.
Mei Kamidani, Ryo Tanaka, Hiroshi Oue, Risa Fukuda, Rena Hashimoto, Ichiro Takeuchi, Takako Yoshioka, Naoya Tonegawa, Akira Ishiguro, Katsuhiro Arai, Kazue Yoshida   +10 more
wiley   +1 more source