Results 121 to 130 of about 130,487 (185)

Possible Role of Human Herpesvirus 6 as a Trigger of Autoimmune Disease

The Scientific World Journal, 2013
Human herpesvirus 6 (HHV-6) infection is common and has a worldwide distribution. Recently, HHV-6A and HHV-6B have been reclassified into two distinct species based on different biological features (genetic, antigenic, and cell tropism) and disease ...
Francesco Broccolo, Lisa Fusetti, Luca Ceccherini-Nelli   +2 more
doaj   +1 more source

MIR376A is a regulator of starvation-induced autophagy [PDF]

, 2013
Background: Autophagy is a vesicular trafficking process responsible for the degradation of long-lived, misfolded or abnormal proteins, as well as damaged or surplus organelles.
Ali Kosar, B Ravikumar, B Teferedegne, BS Zhao, C le Sage, C Macedo, C Nakada, CJ Foley, D Gozuacik, D Nachmani, Deniz Gulfem Ozturk, Devrim Gozuacik, DJ Klionsky, E Chan, EJ Lee, F Wang, G Bjorkoy, G Korkmaz, G Russo, Gozde Korkmaz, H Seitz, H Siomi, HW Platta, I Tanida, J Hildebrand, J Winter, JS Lee, K Breving, K Duskova, KA Tekirdag, Kumsal Ayse Tekirdag, L Zehavi, LB Frankel, LB Frankel, LM Silva, M Kircher, MD Abramoff, N Mizushima, N Mizushima, N Mizushima, O Oral, Osman Ugur Sezerman, P Mestdagh, PM Voorhoeve, R Faraonio, R Scherz-Shouval, RC Russell, RC Wang, RL Skalsky, S Romao, S Sinha, Sebastien Pfeffer, T Wang, TG McDaneld, V Ambros, V Deretic, X Liu, X Zhang, Y Kabeya, Y Kawahara, Y Ohsumi   +60 more
core   +3 more sources

Herpesvirus-host interactions in neurological diseases: the immunogenetic role of HLA-E

Journal of Virology
Human herpesviruses (HHVs) comprise nine pathogenic members, including herpes simplex virus 1, herpes simplex virus 2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, human herpesvirus 6A/B, human herpesvirus 7, and Kaposi’s sarcoma ...
Marianne Graninger, Elisabeth Puchhammer-Stöckl, Hannes Vietzen   +2 more
doaj   +1 more source

Identification of novel CD8+ T cell epitopes in human herpesvirus 6B U11 and U90 [PDF]

, 2015
Human herpesvirus 6B (HHV6B) infects over 90% of the population, and normally establishes a latent infection, where episodes of reactivation are asymptomatic. However, in immunocompromised patients HHV6B reactivation is associated with high morbidity and
Bell, Betts, Boeckh, Bollard, Braun, Cobbold, Crough, Dagna, De Bolle, De Pagter, De Pagter, de Pagter, Dominguez, Dulery, Gerdemann, Glosson, Gompels, Heslop, Hislop, Iampietro, Jaskula, Kern, Khan, Khanna, Leen, Marsh, Martin, Mayne, Nastke, Noriega, Okuno, Papadopoulou, Rammensee, Ressing, Rist, Savoldo, Schmidt, Steven, Sylwester, Takahashi, Tejada-Simon, Walter, Wang, Yakushijin, Yakushijin, Yamanishi, Yasukawa   +46 more
core   +1 more source

The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen presenting cells [PDF]

, 2012
The C-type lectin DC-SIGN expressed on dendritic cells (DCs) facilitates capture and internalization of a plethora of different pathogens. Although it is known that DC-SIGN organizes in nanoclusters at the surface of DCs, the molecular mechanisms ...
Alvarez, Ashby, Bakker, Banchereau, Bonifaz, Cambi, Cambi, Cambi, Cambi, Cambi, Chung, de Bakker, de Witte, Feinberg, Feinberg, Gaborski, Geijtenbeek, Geijtenbeek, Geijtenbeek, Geijtenbeek, Gringhuis, Itano, Itano, Khoo, Koopman, Liu, Liu, Lozach, Lozach, Ludwig, Menon, Mitchell, Neumann, Pohlmann, Puig-Kröger, Rappocciolo, Regan, Serrano-Gómez, Sierra-Filardi, Simmons, Smith, Soilleux, Steinman, Tacken, Tacken, Théry, Trombetta, van Kooyk, Yu, Zhu   +49 more
core   +5 more sources

Workflow to Enhance Virus Reconstitution of Human Herpesvirus 6A (HHV-6A) v1

Human herpesvirus 6A (HHV-6A) is a T-lymphotropic betaherpesvirus that establishes lifelong latency in its host. Virus reactivations have been implicated in several diseases, including multiple sclerosis, encephalitis, myocarditis, and chronic fatigue syndrome, but HHV-6A biology remains poorly understood.
Jana Reich, Dilan Serdar, Jenny Ospina, Yingnan Cheng, Ann-Christin Weißmann, Roosmarijn van der Woude, Georg Beythien, Melissa L. Whyte, Annie Gravel, Thomas Hennig, Louis Flamand, Amy Hudson, Benedikt B. Kaufer   +12 more
openaire   +1 more source

HHV-6A Infection of Endometrial Epithelial Cells Induces Increased Endometrial NK Cell-Mediated Cytotoxicity

Frontiers in Microbiology, 2017
Background: We have recently reported the presence of Human herpesvirus-6A (HHV-6A) DNA in the 43% of endometrial epithelial cells from primary idiopathic infertile women, with no positivity in fertile women.
Elisabetta Caselli, Daria Bortolotti, Roberto Marci, Antonella Rotola, Valentina Gentili, Irene Soffritti, Maria D’Accolti, Giuseppe Lo Monte, Mariangela Sicolo, Isabel Barao, Dario Di Luca, Roberta Rizzo   +11 more
doaj   +1 more source

Transmission dynamics of human herpesvirus 6A, 6B and 7 from whole genome sequences of families. [PDF]

Virol J, 2022
Chrisman BS, He C, Jung JY, Stockham N, Paskov K, Wall DP.   +5 more
europepmc   +1 more source

The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow

Детские инфекции (Москва), 2019
Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible ...
M. Yu. Lysenkova, E. V. Melekhina, N. V. Karazhas, O. A. Svitich, P. A. Veselovsky, T. N. Rybalkina, R. E. Boshyan, V. V. Kosenchuk, A. D. Muzyka, A. V. Gorelov, D. V. Usenko, M. Yu. Ivanova   +11 more
doaj   +1 more source

Human herpesvirus 6A nuclear matrix protein U37 interacts with heat shock transcription factor 1 and activates the heat shock response. [PDF]

J Virol, 2023
Huang JR, Arii J, Hirai M, Nishimura M, Mori Y.   +4 more
europepmc   +1 more source