Results 81 to 90 of about 122,903 (146)

Cytomegalovirus‐Based Viral Vectors Elicit Robust Systemic and Tissue‐Resident Immune Response Against SARS‐CoV‐2 Antigens

European Journal of Immunology, Volume 56, Issue 2, February 2026.
We developed murine CMV‐based viral vectors expressing SARS‐CoV‐2 spike antigen and compared immune response following intraperitoneal and intranasal delivery. Route of vaccine administration shaped antibody and CD8+ T cell response magnitude, kinetics, and tissue residency, highlighting the potential of CMV vectors for induction of protective lung ...
Maja Cokarić Brdovčak, Jelena Materljan Franki, Marko Šustić, Karmela Miklić, Magdalena Medved, Lydia Gaćina, Tina Ružić, Stipan Jonjić, Ilija Brizić, Astrid Krmpotić   +9 more
wiley   +1 more source

GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation.

PLoS ONE, 2014
CD46 and CD134 mediate attachment of Human Herpesvirus 6A (HHV-6A) and HHV-6B to host cell, respectively. But many cell types interfere with viral infection through rapid degradation of viral DNA.
Bhupesh K Prusty, Christine Siegl, Nitish Gulve, Yasuko Mori, Thomas Rudel   +4 more
doaj   +1 more source

Clinico‐Epidemiological and Molecular Evidences for Reactivation of Herpesviruses in Dapsone‐Induced Hypersensitivity Reactions in Nepalese Leprosy Patients: An Observational Study

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
This study found clinical and molecular evidences for the presence of herpesvirus (HHV‐5 and HHV‐6) reactivation during dapsone‐induced hypersensitivity in Nepalese leprosy patients. Reflare of hypersensitivity symptoms occurred on average 20 days after culprit drug cessation.
Divya RSJB Rana, Jivan Shakya, Suwash Baral, Reejana Shrestha, Kishor Koju, Jarina Joshi, Deanna A. Hagge, Mahesh Shah   +7 more
wiley   +1 more source

CURRENT CONCEPT OF HUMAN HERPESVIRUS TYPE 6 INFECTION

Архивъ внутренней медицины, 2016
Human herpes virus type 6 infection is widely distributed. It is extensively studied recent years due to the imperfection of diagnostics, as well as participa- tion in the formation of chronic somatic pathology.
E. V. Melehina, A. D. Muzyka, M. Ju. Kalugina, A. V. Gorelov, O. L. Chugunova   +4 more
doaj   +1 more source

Epstein‐Barr Virus Infection at Single‐Cell Resolution

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Epstein‐Barr virus (EBV) infection has been studied at single‐cell resolution for six decades and counting. Such investigations can reveal virus‐host interactions and their dependence on viral strain, cellular niche, infection program, immune response regulation, and time.
Elliott D. SoRelle
wiley   +1 more source

Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A

Virology, 2012
KSHV inflammatory cytokine syndrome (KICS) is a newly described condition characterized by systemic illness as a result of systemic, lytic KSHV infection. We used Illumina sequencing to establish the DNA vironome of blood from such a patient. It identified concurrent high-level viremia of human herpesvirus (HHV) 8 and 6a. The HHV8 plasma viral load was
Tamburro, Kristen M., Yang, Dongmei, Poisson, Jessica, Fedoriw, Yuri, Roy, Debasmita, Lucas, Amy, Sin, Sang-Hoon, Malouf, Nadia, Moylan, Vincent, Damania, Blossom, Moll, Stephan, van der Horst, Charles, Dittmer, Dirk P.   +12 more
openaire   +2 more sources

Detection of human herpesvirus 7 in conjunctival samples collected from individuals recovering from conjunctivitis

Frontiers in Ophthalmology
PurposeAlthough it is often reported that adenovirus is the most common etiology for infectious conjunctivitis, a recent multi-center clinical study found that adenovirus was confirmed by polymerase chain reaction in only 16% of cases presenting with ...
Andrew T.E. Hartwick, Christina E. Morettin, Jennifer S. Harthan, Meredith Whiteside, Ellen Shorter, Spencer D. Johnson, Mary K. Migneco, Christian K. Olson, Julia B. Huecker, Tammy Than, Mae O. Gordon   +10 more
doaj   +1 more source

Possible Role of Human Herpesvirus 6 as a Trigger of Autoimmune Disease

The Scientific World Journal, 2013
Human herpesvirus 6 (HHV-6) infection is common and has a worldwide distribution. Recently, HHV-6A and HHV-6B have been reclassified into two distinct species based on different biological features (genetic, antigenic, and cell tropism) and disease ...
Francesco Broccolo, Lisa Fusetti, Luca Ceccherini-Nelli   +2 more
doaj   +1 more source

Herpesvirus-host interactions in neurological diseases: the immunogenetic role of HLA-E

Journal of Virology
Human herpesviruses (HHVs) comprise nine pathogenic members, including herpes simplex virus 1, herpes simplex virus 2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, human herpesvirus 6A/B, human herpesvirus 7, and Kaposi’s sarcoma ...
Marianne Graninger, Elisabeth Puchhammer-Stöckl, Hannes Vietzen   +2 more
doaj   +1 more source

HHV-6A Infection of Endometrial Epithelial Cells Induces Increased Endometrial NK Cell-Mediated Cytotoxicity

Frontiers in Microbiology, 2017
Background: We have recently reported the presence of Human herpesvirus-6A (HHV-6A) DNA in the 43% of endometrial epithelial cells from primary idiopathic infertile women, with no positivity in fertile women.
Elisabetta Caselli, Daria Bortolotti, Roberto Marci, Antonella Rotola, Valentina Gentili, Irene Soffritti, Maria D’Accolti, Giuseppe Lo Monte, Mariangela Sicolo, Isabel Barao, Dario Di Luca, Roberta Rizzo   +11 more
doaj   +1 more source