Results 151 to 160 of about 74,702 (247)

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, Volume 178, Issue 4, Page 685-703, August 2026.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro, Mª. Lourdes Ruiz Rebollo, Paloma Cal‐Sabater, Elisa Arribas‐Rodríguez, Álvaro Martín‐Muñoz, Alejandro Gonzalez del Hierro, Marina Perez Mazzali, Jessica Matesanz‐Isabel, Hugo Gonzalo‐Benito, Sara Cuesta‐Sancho, David Bernardo   +10 more
wiley   +1 more source

Multistep coevolution of HIV-1 and human leukocyte antigen-C-restricted HIV-1-specific CD8⁺ T cells and the association with disease progression. [PDF]

PNAS Nexus
Chikata T, Akahoshi T, Zhang Y, Nguyen HT, Oka S, Gatanaga H, Takiguchi M.   +6 more
europepmc   +1 more source

Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Despite the presence of licensed vaccines and therapeutics, influenza viruses remain a major public health concern, as they cause seasonal respiratory infections and pose a pandemic threat through the emergence of zoonotic strains. Although neutralizing antibodies elicited by seasonal vaccination constitute a primary defense against infection,
Yu Adachi, Yoshimasa Takahashi
wiley   +1 more source

Generation of therapeutic T cells from human induced pluripotent stem cells. [PDF]

Inflamm Regen
Wang B, Kaneko S.
europepmc   +1 more source

Anti‐Modified Protein Antibodies in Rheumatoid Arthritis: Pathogenic, Protective, or Passive Bystander?

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT The presence of anti‐modified protein antibodies (AMPA) is a hallmark of rheumatoid arthritis (RA). AMPA recognize post‐translationally modified proteins and are cross‐reactive. AMPA include anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA).
Amber‐Sarai F. L. Stalman, Diane van der Woude   +1 more
wiley   +1 more source

Tuning the Affinity of Chimeric Antigen Receptors Enhances the Function of Human Engineered Regulatory T Cells. [PDF]

Eur J Immunol
Kurt AS, Elgosbi M, Kodela E, Landmann E, Ruiz P, Zen Y, Torres-Yaguana J, Puttick A, Bustamante Q, Sharjeel M, Murshid H, Martinez-Llordella M, Sanchez-Fueyo A.   +12 more
europepmc   +1 more source

iSPHYNCS: Unsupervised Clustering in Questionnaires and Metadata Reveals Distinct Subtypes in the Narcolepsy Borderland

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
Study overview and clustering results in the iSPHYNCS cohort. Participant demographics are summarized in a baseline table. Questionnaire data and metadata were processed through an unsupervised clustering pipeline. A Sankey plot illustrates individual assignment across clusters by diagnostic group.
Rafael Morand, Livia Fregolente, Julia van der Meer, Elena S. Wenz, Annina Helmy, Lorenzo Brigato, Jan D. Warncke, Kseniia Zub, Ramin Khatami, Zhongxing Zhang, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Ulf Kallweit, Gert Jan Lammers, Athina Tzovara, Claudio L. A. Bassetti, Stavroula Mougiakakou, Markus H. Schmidt   +19 more
wiley   +1 more source

Differences in Clinical Manifestations and Islet Autoantibodies by Age in Adult-Onset Type 1 Diabetes. [PDF]

Diabetes Care
Karakus KE, Clayton MG, Baschal EE, McDaniel KA, Yu L, Haider Z, Polsky S, Akturk HK, Gottlieb PA, Garg SK, Michels AW.   +10 more
europepmc   +1 more source

Ubiquitination‐Related Diagnostic Biomarkers for Diabetic Nephropathy: Insights From Multiomic Analysis, Drug Docking, and Experimental Validation

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
The Graphical Abstract demonstrates our research approach. Use GEO database to screen differentially expressed genes (DEGs), and weighted gene co expression network analysis (WGCNA) to identify ubiquitination related gene modules. The LASSO logistic regression and support vector machine recursive feature elimination (SVM‐RFE) algorithm is used to ...
Ting Dong, Miao Hu, Haibo Yu, Ling Zhou, Qing Qiao   +4 more
wiley   +1 more source