Results 211 to 220 of about 74,702 (247)

Human leukocyte antigen-B phenotype and minimal residual disease in chronic myeloid leukemia patients treated with imatinib: Is there an association?

, 2020
Background: Human leukocyte antigen (HLA) phenotype is a prognostic marker of cancer immunotherapy, and the expression profile of its alleles is associated with therapeutic rate.
Elham H Hadad, A. Ehsanpour, T. Vosoughi, N. Saki   +3 more
semanticscholar   +1 more source

P171 Clinical and genetic profiling of first-degree relatives of Human Leukocyte Antigen-B*27-positive spondyloarthritis patients

Rheumatology
Spondyloarthritis (SpA), a HLA-B*27-linked disease, affects 0.7-1.0 per 1,000 in India, 0.2-0.5% globally, with their first-degree relatives (FDRs) at a 20-27% lifetime risk if B*27 positive.
V. Koneru, C. Mariaselvam, Gayathri K Abhilash, Subin Philip, Rehana Khadar, K. G. Chengappa, M. Thabah, V. Negi   +7 more
semanticscholar   +1 more source

HLA-B*27 subtypes and their implications in the pathogenesis of ankylosing spondylitis.

Gene, 2018
Ankylosing spondylitis (AS) is a highly heritable kind of arthritis that affects the vertebral column. AS risk has been associated strongly with Human leukocyte antigen (HLA)-B*27.
Navid Dashti, M. Mahmoudi, S. Aslani, A. Jamshidi   +3 more
semanticscholar   +1 more source

Decoding human leukocyte antigen Beta-27; its active alleles in Ankylosing Spondylitis and computational insights of potential inhibitors: HLA-B27 in AS; its variants and inhibitors.

Human Immunology
OBJECTIVES This study aimed to determine the diverse inborn and adventitious variables that contribute to the rise of Ankylosing Spondylitis (AS) and to elucidate the genotypic study of HLA-B*27 alleles along with sub-alleles and in-silico inhibition of ...
H. Altaf, Muhammad Adil, Nuha Anajirih, Muhammad Ahmed Saeed, Nageen Hussain   +4 more
semanticscholar   +1 more source

Clinical correlates of HLA‐B*27 and its subtypes in enthesitis‐related arthritis variant of juvenile idiopathic arthritis in south Indian Tamil patients

International Journal of Rheumatic Diseases, 2019
The aim of the study was to assess the distribution of human leukocyte antigen (HLA)‐B*27 subtypes and its correlation with disease phenotypes in children with enthesitis‐related arthritis variant of juvenile idiopathic arthritis (JIA‐ERA).
C. Kavadichanda, G. Seth, Gunjan Kumar, R. Gulati, V. Negi   +4 more
semanticscholar   +1 more source

Emerging biochemical, microbial and immunological evidence in the search for why HLA-B*27 confers risk for spondyloarthritis

Cell Chemical Biology
Summary The strong association of the human leukocyte antigen B*27 alleles (HLA-B*27) with spondyloarthritis and related rheumatic conditions has long fascinated researchers, yet the precise mechanisms underlying its pathogenicity remain elusive.
Eric M Brown, Phuong N.U. Nguyen, Ramnik J. Xavier   +2 more
semanticscholar   +1 more source

The Structural Basis for Recognition of Human Leukocyte Antigen Class I Molecules by the Pan-HLA Antibody W6/32.

Journal of Immunology
The central immunological role of HLA class I (HLA-I) in presenting peptide Ags to cellular components of the immune system has been the focus of intense study for >60 y.
P. Pymm, Philippa M. Saunders, Sushma Anand, B. MacLachlan, Camilla Faoro, Corinne R Hitchen, J. Rossjohn, Andrew G. Brooks, J. Vivian   +8 more
semanticscholar   +1 more source

The association between refractory plantar fasciitis and insertional Achilles tendinopathy and peripheral spondyloarthritis: a report of human leukocyte antigen B-27 investigation and treatment outcome

International Orthopaedics, 2023
Young Ho Jung, J. Suh, J. Choi
semanticscholar   +1 more source

Association between HLA-B*27:04 and genetic susceptibility to ankylosing spondylitis in Hunan Province.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023
Xiaofang Lu, Ling Wan, K. Zou, Liang Tan, Quan Zhu, Rongjiao Liu, Xiangli Yin, Zixuan Song, Leiyan Wei, Zhiqing Xiang, Yizhou Zou   +10 more
semanticscholar   +1 more source

HLA-C*03:04:01 and HLA-B*15:18:01 but not HLA-DQA1*05 associated with anti- tumor necrosis factor antibody formation in Taiwanese inflammatory bowel disease patients

World Journal of Gastroenterology
BACKGROUND Anti-drug antibodies (ADAs) can reduce the effectiveness of biologics. While human leukocyte antigen (HLA)-DQA1*05 allele is linked to ADA formation in European Crohn’s disease patients, its relevance in non-European populations remains ...
Meng-Tzu Weng, C. Yao, Wei-Chen Lin, S. Lai, C. Tung, Chun-Ying Wang, J. Wong, Pei-Lung Chen, Shu-Chen Wei   +8 more
semanticscholar   +1 more source