Results 201 to 210 of about 70,114,613 (255)

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

open access: yesAdvanced Science, Volume 13, Issue 60, 28 October 2026.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv   +16 more
wiley   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu   +7 more
wiley   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li   +11 more
wiley   +1 more source

Identifying Co‐Expressed lncRNAs Correlated With Traits of Interest in an Animal Model for Metabolic Diseases in Humans

open access: yesAnimal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Nutrigenomics investigates how nutrients modulate gene expression. Among them, fatty acids (FA) play important roles in regulating gene transcription, while long non‐coding RNAs (lncRNAs) may be associated with gene regulation and metabolic diseases.
Lucas Echevarria Nascimento   +11 more
wiley   +1 more source

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

open access: yesAnnals of Neurology, Volume 100, Issue 4, Page 793-807, October 2026.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy