Results 181 to 190 of about 50,120 (254)

Metabolic Stability and Metabolite Identification of N-Ethyl Pentedrone Using Rat, Mouse and Human Liver Microsomes. [PDF]

Pharmaceutics
Godoi AB, Antunes NJ, Cunha KF, Martins AF, Huestis MA, Costa JL.   +5 more
europepmc   +1 more source

Inhibitory Effects of Schisandra Lignans on Cytochrome P450s and Uridine 5'-Diphospho-Glucuronosyl Transferases in Human Liver Microsomes. [PDF]

Pharmaceutics, 2021
Seo HJ, Ji SB, Kim SE, Lee GM, Park SY, Wu Z, Jang DS, Liu KH.   +7 more
europepmc   +1 more source

A new approach in pediatric drug design : the development of a pediatric pig model, part II : the maturation of hepatic cytochrome P450 enzymes using enzyme activity and proteomics [PDF]

, 2017
Croubels, Siska, De Bock, Lies, Deforce, Dieter, Devreese, Mathias, Gasthuys, Elke, Millecam, Joske, Van Bocxlaer, Jan   +6 more
core   +1 more source

An Ultra-Fast Validated Green UPLC-MS/MS Approach for Assessing Revumenib in Human Liver Microsomes: In Vitro Absorption, Distribution, Metabolism, and Excretion and Metabolic Stability Evaluation. [PDF]

Medicina (Kaunas)
Attwa MW, Abdelhameed AS, Kadi AA.
europepmc   +1 more source

Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes. [PDF]

Front Pharmacol, 2022
Kapelemera AM, Uang YS, Wang LH, Wu TY, Lee FY, Tai L, Wang CC, Lee CJ.   +7 more
europepmc   +1 more source

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes. [PDF]

Mol Pharm, 2021
Wegler C, Matsson P, Krogstad V, Urdzik J, Christensen H, Andersson TB, Artursson P.   +6 more
europepmc   +1 more source

Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes. [PDF]

Pharm Biol, 2020
Wang M, Jiang W, Zhou J, Xue X, Yin C.
europepmc   +1 more source

Comparison of reversed-phase, hydrophilic interaction, and porous graphitic carbon chromatography columns for an untargeted toxicometabolomics study in pooled human liver microsomes, rat urine, and rat plasma. [PDF]

Metabolomics
Hemmer S, Manier SK, Wagmann L, Meyer MR.   +3 more
europepmc   +1 more source

Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes. [PDF]

Drug Metab Dispos, 2022
Bansal S, Paine MF, Unadkat JD.
europepmc   +1 more source

Identification of cytochrome P450 isoenzymes involved in the metabolism of 23-hydroxybetulinic acid in human liver microsomes. [PDF]

Pharm Biol, 2020
Zhou Y, Wen J, Wang G.
europepmc   +1 more source