Results 61 to 70 of about 1,240,536 (340)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Better Control of Holder Pasteurization Results in Higher Retention of Human Milk Lactoferrin, IgA, and Lysozyme

Frontiers in Pediatrics, 2018
Background: Holder pasteurization is commonly used in milk banks. We previously reported that the pattern of temperature and time may be different according to the pasteurizer used.Aim: The aim of our study was to assess the variances in pasteurization ...
Rachel Buffin, Rachel Buffin, Stéphane Hays, Jocelyne Drai, Marie-Nathalie Sarda, Jean-Charles Picaud, Jean-Charles Picaud, Jean-Charles Picaud   +7 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Early infant feeding and adiposity risk: from infancy to adulthood [PDF]

, 2014
Introduction: Systematic reviews suggest that a longer duration of breast-feeding is associated with a reduction in the risk of later overweight and obesity.
Beilin, L J, Chivers, Paola, Hands, Beth, Huang, R C, Jacoby, P, Koletzko, B V, Marsh, J A, Mori, T A, Oddy, W H, Pennell, C E, Rzehak, P   +10 more
core   +2 more sources

Understanding the current and future usage of donor human milk in hospitals: An online survey of UK neonatal units

Maternal and Child Nutrition, 2023
The use of donor human milk (DHM) where there is a shortfall of maternal milk can benefit both infant and maternal outcomes but DHM supply is not always assured.
Natalie S. Shenker, Samantha Griffin, Jonathan Hamill‐Keays, Merran Thomson, Judith Simpson, Gillian Weaver   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The Unsung Heroes: The Profile of the Donor at a Southern Italian Milk Bank and Driving Factors in Human Milk Donation

Children
Background/Objectives: One of the most effective strategies to mitigate morbidity associated with preterm birth is the use of human milk. The first choice is the mother’s milk; if that is not available, human milk donated to milk banks is the second ...
Pasqua Anna Quitadamo, Laura Comegna, Federica Zambianco, Giuseppina Palumbo, Massimiliano Copetti, Maria Assunta Gentile, Antonio Mondelli, Isadora Beghetti, Luigi Corvaglia   +8 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants. [PDF]

, 2017
Attempts to alter intestinal dysbiosis via administration of probiotics have consistently shown that colonization with the administered microbes is transient. This study sought to determine whether provision of an initial course of Bifidobacterium longum
Andra A. Hutton, Bethany M. Henrick, Carlito B. Lebrilla, Claire A. Shaw, Daniela Barile, David A. Mills, Gege Xu, Giorgio Casaburi, J. Bruce German, Jasmine C. C. Davis, Jennifer T. Smilowitz, Lindsey N. Contreras, Mark A. Underwood, Michelle C. Palumbo, Rosa Krajmalnik-Brown, Samara L. Freeman, Steven A. Frese   +16 more
core   +2 more sources

Recommendations for the Establishment and Operation of Human Milk Banks in Europe: A Consensus Statement From the European Milk Bank Association (EMBA)

Frontiers in Pediatrics, 2019
Objectives: To develop recommendations from the European Milk Bank Association (EMBA) for the establishment and operation of human milk banks (HMB) in Europe.Method: A working group comprising members of the EMBA was convened in 2015 to develop Europe ...
Gillian Weaver, Enrico Bertino, Corinna Gebauer, Anne Grovslien, Radmila Mileusnic-Milenovic, Sertac Arslanoglu, Debbie Barnett, Clair-Yves Boquien, Rachel Buffin, Antoni Gaya, Guido E. Moro, Aleksandra Wesolowska, Aleksandra Wesolowska, Jean-Charles Picaud, Jean-Charles Picaud   +14 more
doaj   +1 more source