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Oligosaccharides of Human Milk
Nature, 1957THE presence of fucose as a constituent sugar in oligosaccharides obtained from human milk was reported by Kuhn1 in 1952. Since that time Kuhn and his associates have characterized four oligosaccharides from this source, in all of which fucose is found: a trisaccharide, fucosido-lactose; two pentasaccharides referred to as lacto-N-fucopentaoses I and ...
F. E. Hytten, F. H. Malpress
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2001
Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
M. Hilty +4 more
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Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
M. Hilty +4 more
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Human milk and related oligosaccharides as prebiotics
Current Opinion in Biotechnology, 2013Human milk oligosaccharides (HMO) are believed to have a range of biological activities beyond providing nutrition to the infant. Principal among these is that they may act as prebiotics. Prebiotics are dietary ingredients, usually oligosaccharides that provide a health benefit to the host mediated by the modulation of the human gut microbiota.
Robert A. Rastall, Daniela Barile
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Biotechnological production of human milk oligosaccharides
Biotechnology Advances, 2012Human milk contains a large variety of oligosaccharides (HMOs) that have the potential to modulate the gut flora, affect different gastrointestinal functions, and influence inflammatory processes. This review introduces the recent advances in the microbial and coupled enzymatic methods to produce HMOs with grouping them into trisaccharides ...
Nam Soo Han +4 more
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Human milk oligosaccharides: Only the breast
Journal of Paediatrics and Child Health, 1997Abstract: Over 100 years ago it was first deduced that a major component of human milk must be an unidentified carbohydrate that was not found in cows milk. At first this was thought to be a form of lactose and was called gynolactose. We now know that this was not a single carbohydrate but a complex mixture of approximately 130 different ...
J B Miller, P McVeagh
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Human Milk Oligosaccharides as Prebiotics
2014The characteristic composition of the intestinal microbiota of breast-fed neonates is due to the presence of particular substances in human milk. This chapter aims to identify the components that are able to promote the prebiotic effect in human milk, and is oriented towards modifying the composition of infant formulas in order to obtain an intestinal ...
Giovanni V. Coppa, Orazio Gabrielli
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The functional biology of human milk oligosaccharides
Early Human Development, 2015Human milk oligosaccharides (HMOs) are a group of complex sugars that are highly abundant in human milk, but currently not present in infant formula. More than a hundred different HMOs have been identified so far. The amount and composition of HMOs are highly variable between women, and each structurally defined HMO might have a distinct functionality.
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Regulatory Aspects of Human Milk Oligosaccharides
2017Human milk oligosaccharides are key components of human milk and appear in various compositions and concentrations in all human milks. In regulatory sense human milk oligosaccharides are classified as novel foods or novel food ingredients requiring safety assessment.
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Bifidobacterial utilization of human milk oligosaccharides
International Journal of Food Microbiology, 2011A promising strategy to improve health is the rational manipulation of one's beneficial microbiota via dietary interventions. This is observed in nature where specific bifidobacteria utilize human milk oligosaccharides (HMOs) that are encountered within the breast-fed infant colon. Bifidobacterium longum subsp.
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Human Milk Oligosaccharides: Structure and Functions
2020Oligosaccharides are a group of complex glycans that are present in the milk of most mammals. However, human milk is unique as the concentrations of human milk oligosaccharides (HMOs) are much higher than those of other mammals, and their structural composition is more complex and varies between women.
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