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Human milk and related oligosaccharides as prebiotics

open access: yesCurrent Opinion in Biotechnology, 2013
Human milk oligosaccharides (HMO) are believed to have a range of biological activities beyond providing nutrition to the infant. Principal among these is that they may act as prebiotics. Prebiotics are dietary ingredients, usually oligosaccharides that provide a health benefit to the host mediated by the modulation of the human gut microbiota.
Daniela, Barile, Robert A, Rastall
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Human milk oligosaccharides: prebiotics and beyond

Nutrition Reviews, 2009
Human milk oligosaccharides (HMO) are complex glycans that are present at very high concentrations in human milk but not in infant formula. The significant energy expended by mothers to make these complex glycans suggests they must be important. How do maternal HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary gland? How
Lars Bode, Bode Lars
exaly   +3 more sources

Goat Milk Oligosaccharides: Their Diversity, Quantity, and Functional Properties in Comparison to Human Milk Oligosaccharides [PDF]

open access: yesJournal of Agricultural and Food Chemistry, 2020
Human milk is considered the golden standard in infant nutrition. Free oligosaccharides in human milk provide important health benefits. These oligosaccharides function as prebiotics, immune modulators, and pathogen inhibitors and were found to improve ...
Sander S van Leeuwen   +2 more
exaly   +2 more sources

Oligosaccharides of Human Milk

Nature, 1957
THE presence of fucose as a constituent sugar in oligosaccharides obtained from human milk was reported by Kuhn1 in 1952. Since that time Kuhn and his associates have characterized four oligosaccharides from this source, in all of which fucose is found: a trisaccharide, fucosido-lactose; two pentasaccharides referred to as lacto-N-fucopentaoses I and ...
F H, MALPRESS, F E, HYTTEN
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Characterization and Quantification of Oligosaccharides in Human Milk and Infant Formula

open access: yesJournal of Agricultural and Food Chemistry, 2018
Oligosaccharides are known to affect the health of infants. The analysis of these complex molecules in (human) milk samples requires state-of-the-art techniques.
Apichaya Bunyatratchata   +2 more
exaly   +2 more sources

Human Milk Oligosaccharides and Immune System Development [PDF]

open access: yesNutrients, 2018
Maternal milk contains compounds that may affect newborn immunity. Among these are a group of oligosaccharides that are synthesized in the mammary gland from lactose; these oligosaccharides have been termed human milk oligosaccharides (HMOs).
Julio Plaza-Díaz   +2 more
exaly   +3 more sources

Human milk oligosaccharides

Journal of Pediatric Gastroenterology and Nutrition, 2016
Human milk oligosaccharides are very complex molecules and hence are difficult to synthesize. These specialty carbohydrates are consequently very expensive and not available in sufficient quantities. Enzymatic synthesis is efficient for relatively simple carbohydrates but cannot be used for more complex carbohydrates.
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Human milk oligosaccharides: Only the breast

Journal of Paediatrics and Child Health, 1997
Abstract: Over 100 years ago it was first deduced that a major component of human milk must be an unidentified carbohydrate that was not found in cows milk. At first this was thought to be a form of lactose and was called gynolactose. We now know that this was not a single carbohydrate but a complex mixture of approximately 130 different ...
P, McVeagh, J B, Miller
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Human Milk Oligosaccharides

2001
Human milk is a unique reservoir of oligosaccharides. The presence of many of these oligosaccharides is determined genetically and is related to the Lewis blood group and secretor antigen status of each donor. A method to quantitate neutral human milk oligosaccharides was developed.
R. Erney   +4 more
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Bifidobacterial utilization of human milk oligosaccharides

International Journal of Food Microbiology, 2011
A promising strategy to improve health is the rational manipulation of one's beneficial microbiota via dietary interventions. This is observed in nature where specific bifidobacteria utilize human milk oligosaccharides (HMOs) that are encountered within the breast-fed infant colon. Bifidobacterium longum subsp.
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