Results 41 to 50 of about 18,561 (232)

Studies and Application of Sialylated Milk Components on Regulating Neonatal Gut Microbiota and Health

Frontiers in Nutrition, 2021
Breast milk is rich in sialic acids (SA), which are commonly combined with milk oligosaccharides and glycoconjugates. As a functional nutrient component, SA-containing milk components have received increasing attention in recent years.
Yushuang Wang, Xiaolei Ze, Binqi Rui, Xinke Li, Nina Zeng, Jieli Yuan, Wenzhe Li, Jingyu Yan, Ming Li   +8 more
doaj   +1 more source

Efforts to emulate human milk oligosaccharides [PDF]

British Journal of Nutrition, 2007
Research on human milk oligosaccharides (HMO) began with the characterisation of their chemical structures and is now focused on the elucidation of their biological roles. Previously, biological effects could only be investigated with fractions or structures isolated from breast milk; consequently, clinical observations were limited to comparisons ...
Rosa María, Espinosa, Martha, Taméz, Pedro, Prieto   +2 more
openaire   +2 more sources

Differential transcriptional response of Bifidobacterium longum to human milk, formula milk and galactooligosaccharide

, 2008
In order to gain insight into the effects of human breast milk on the development of the intestinal bifidobacteria and associated health effects, the transcriptome of Bifidobacterium longum LMG 13197 grown in breast milk and formula milk containing ...
Vos, W.M., de, Malinen, E., Vaughan, E.E., Gonzalez, R., E. E. Vaughan, E. Malinen, R. Gonzalez, de Vos, W.M., W. M. de Vos, E. S. Klaassens, Klaassens, E.S.   +10 more
core   +1 more source

Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration

Nature Communications, 2022
Human milk oligosaccharides are fundamental to infant health. Here the authors deploy a multi-omics systems biology approach to elucidate their biosynthetic network, including the associated enzymes and likely structures of ambiguous oligosaccharides.
Benjamin P. Kellman, Anne Richelle, Jeong-Yeh Yang, Digantkumar Chapla, Austin W. T. Chiang, Julia A. Najera, Chenguang Liang, Annalee Fürst, Bokan Bao, Natalia Koga, Mahmoud A. Mohammad, Anders Bech Bruntse, Morey W. Haymond, Kelley W. Moremen, Lars Bode, Nathan E. Lewis   +15 more
doaj   +1 more source

Breast Milk from Tanzanian Women has Divergent Effects on Cell-Free and Cell-Associated HIV-1 Infection in Vitro. [PDF]

, 2012
Transmission of HIV-1 during breastfeeding is a significant source of new pediatric infections in sub-Saharan Africa. Breast milk from HIV-positive mothers contains both cell-free and cell-associated virus; however, the impact of breast milk on HIV-1 ...
Ruth I Connor, Alexandra L Howell, Molly L Housman, Lee, F.V, Housman, M.L., Zain-Ul-Abideen Muhammad, Frederick V Lee, Zain-Ul-Abideen, M., Connor, R.I, Connor Ruth I., Zain-Ul-Abideen, Muhammad, Lyimo, M.A., Howell, Alexandra L, Lyimo, Magdalena A, Magdalena A Lyimo, Howell Alexandra L., Housman, Molly L, Mosi, M.N, Muhammad Zain-Ul-Abideen, Howell, A.L, Lee, Frederick V, Mosi, Matilda Ngarina, Matilda Ngarina Mosi, Connor, Ruth I, Lyimo Magdalena A., Housman Molly L., Mosi Matilda Ngarina, Lee Frederick V.   +27 more
core   +1 more source

EFFICIENT EXTRACTION OF 2’-FUCOSYLLACTOSE FROM HUMAN MILK: PARAMETER OPTIMIZATION WITH SURFACE RESPONSE [PDF]

Química Nova
2’-Fucosyllactose (2’-FL) is the predominant oligosaccharide in human milk, responsible for important infant biological functions. Its quantification requires specific extraction and analysis methods, but current techniques use toxic solvents for ...
Elienae da Silva Gomes, Eloize Silva Alves, Patricia Daniele Silva Santos, Marcela de Souza Zangirolami, Oscar Oliveira Santos   +4 more
doaj   +1 more source

Profiles of Human Milk Oligosaccharides and Production of Some Human Milk Oligosaccharides in Transgenic Animals [PDF]

Advances in Nutrition, 2012
During the decade of the 1990s and the first years of the current century, our group embarked on a project to study and synthesize human milk oligosaccharides. This report describes 2 unexpected collateral observations from that endeavor. The first observation was the detection and confirmation of 2 rare neutral human milk oligosaccharides profiles ...
openaire   +2 more sources

Maternal diet alters human milk oligosaccharide composition with implications for the milk metagenome

Scientific Reports, 2020
Human milk is the optimal nutrition source for infants, and oligosaccharides represent the third most abundant component in milk after lactose and fat. Human milk oligosaccharides (HMO) are favorable macromolecules which are, interestingly, indigestible ...
Maxim D. Seferovic, Mahmoud Mohammad, Ryan M. Pace, Melinda Engevik, James Versalovic, Lars Bode, Morey Haymond, Kjersti M. Aagaard   +7 more
doaj   +1 more source

Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides

, 2016
Histo-blood group antigens (HBGAs) are important binding factors for norovirus infections. We show that two human milk oligosaccharides, 2'-fucosyllactose (2'FL) and 3-fucosyllactose (3FL), could block norovirus from binding to surrogate HBGA samples. We
Koromyslova, A, Jennewein, S, Hansman, GS, Schroten, H, Singh, BK, Weichert, S, Hansman, S   +6 more
core   +1 more source

Human norovirus interactions with histo-blood group antigens and human milk oligosaccharides

, 2016
Human noroviruses interact with both human histo-blood group antigens (HBGAs) and human milk oligosaccharides (HMOs). The former is believed to be important for a virus infection, while the latter might act as a natural decoy in the host during an ...
Hansman, GS, Hanisch, FG, Schroten, H
core   +1 more source