Results 31 to 40 of about 8,090,431 (285)
Frequency of human platelet antigens −1 to −5 and −15 in Turkmen blood donors
Background: Due to the presence of platelet antigen polymorphisms, human platelet membrane glycoproteins can be identified as an alloantigen or autoantigen.
Maedeh Nozarimirarkolaei +5 more
doaj +1 more source
Analysis and prospect of platelet compatible transfusion
Platelet compatible transfusion can effectively solve the immune mediated platelet transfusion refractoriness (PTR), save platelet resources and improve blood safety.
Faming ZHU, Wei MAO, Zhixin ZHANG
doaj +1 more source
Immunocytochemical Studies on Platelets. The Demonstration of a Common Antigen in Human Platelets and Megakaryocytes [PDF]
Abstract By means of the fluorescent antibody technic of Coons and Kaplan it was possible to demonstrate a common antigenic structure in human platelets and megakaryocytes, both in nonthrombocytopenic cases and in cases with idiopathic thrombocytopenic purpura.
J J, VAZQUEZ, J H, LEWIS
openaire +2 more sources
Background Neonatal alloimmune thrombocytopenia is mostly due to the presence of maternal antibodies against the fetal platelet antigen HPA-1a on the platelet integrin GPIIb-IIIa.
Julien Thibaut +3 more
doaj +1 more source
Polymorphism in human platelet antigen (HPA)-1 and HPA-3 (GPIIb/IIIa), HPA-2 (GPIb/IX), HPA-4 (GPIIIa), HPA-5 (GPIa/IIa), & HPA-15 (CD109) was investigated in 86 COVID-19-infected patients with thrombocytopenia (Group A) and 136 COVID-19-infected ...
Kazem Ghaffari +9 more
doaj +1 more source
Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture [PDF]
Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric oxide synthase
Damian J Murphy +17 more
core +1 more source
Calcium sequestration by human platelet acidic organelles is regulated by the actin cytoskeleton and autocrine 5-hydroxytryptamine [PDF]
Human platelets regulate agonist-evoked Ca2+ signalling through Ca2+ release from and sequestration into acidic organelles. Previous studies have pharmacologically characterised the presence of a Ca2+-H+ exchanger in these organelles.
Harper
core +1 more source
Localization of platelet antigens in human kidney disease
The localization of a platelet antigen or antigens kidneys from 106 patients with renal disease was evaluated with immunofluorescent microscopy by using a rabbit antibody to human platelets. The antiplatelet IgG fixed to the surface membrane of platelets did not react with erythrocytes, leukocytes, plasma, normal kidney, or a variety of normal tissue ...
Miller, Kenneth +2 more
openaire +2 more sources
Background: Platelet (PLT) transfusion has been a crucial for clinical blood transfusion and bleeding prophylaxis. Identification of antibody against PLT-specific antigen is important for accurately diagnosing posttransfusion purpura, neonatal alloimmune
Qin-Qin Ma +4 more
doaj +1 more source
Alloimmune thrombocytopenia is the most common cause of severe thrombocytopenia and intracranial bleed in the perinatal period, resulting from placental transfer of maternal platelet antibodies directed against the paternal-derived fetal platelet ...
H A Venkatesh +3 more
doaj +1 more source

