Results 21 to 30 of about 8,090,431 (285)

Platelet antibody detection by flow cytometry: an effective method to evaluate and give transfusional support in platelet refractoriness

Revista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND: Immune platelet refractoriness is mainly caused by human leukocyte antigen antibodies (80-90% of cases) and, to a lesser extent, by human platelet antigen antibodies.
Carolina Bonet Bub, Beatriz Moraes Martinelli, Thayna Mendonca Avelino, Ana Claudia Goncalez, Maria de Lourdes Barjas-Castro, Vagner Castro   +5 more
doaj   +1 more source

The polymorphism of HPA-1-6w, HPA-15 and HPA-32bw-35bw in platelet donors from Deyang, Sichuan

Zhongguo shuxue zazhi, 2022
Objective To explore the polymorphism of HPA-1-6w, HPA-15 and 32bw-35bw in platelet donors in Deyang, Sichuan, and estimate whether to include the detection of 32bw-35bw in the platelet bank. Methods Polymerase chain reaction with sequenced based typing (
Qilu LYU, Xiuyun LIAO, Xin JI, Li YUAN, Liqiong QIAN, Shichun SHU, Qiang CHEN, Jue WANG   +7 more
doaj   +1 more source

Determination of platelet antigens and glycoproteins in the human fetus [PDF]

Blood, 1986
The autosomal recessive transmission of Glanzmann's thrombasthenia (GT) and Bernard-Soulier syndrome (BSS), together with requests of families who already had children with these diseases, prompted us to investigate the feasibility of their antenatal diagnosis. The preliminary step leading to the early detection of GT or BSS was to characterize, in the
Y, Gruel, B, Boizard, F, Daffos, F, Forestier, J, Caen, J L, Wautier   +5 more
openaire   +3 more sources

Factor XI antigen and activity in human platelets [PDF]

Blood, 1982
Abstract Washed platelets, contaminated with less than 0.20% plasma factor XI, were examined for the presence of factor XI antigen and activity. These platelets contained a factor-XI-like coagulant activity (0.67 +/- 0.11 U/10(11) platelets) that remained constant after successive washes.
G P, Tuszynski, S J, Bevacqua, A H, Schmaier, R W, Colman, P N, Walsh   +4 more
openaire   +3 more sources

Applicability of an instrument to identify human leukocyte antigen-compatible donors for platelet transfusions

Hematology, Transfusion and Cell Therapy, 2018
Background: The selection of compatible human leukocyte antigen platelets has been associated with improved platelet increments. Therefore, an effective strategy would be the selection of donors who are genetically compatible according to the human ...
Millena Gomes Ferreira, Fernanda Bernadelli De Vito, Aline Aparecida Ferreira, Carolina Bonet Bub, Fernando Antônio Vinhal dos Santos, Adilson Botelho Filho, Sheila Soares Silva, Helio Moraes-Souza   +7 more
doaj   +1 more source

Study on the extensibility of platelet donor gene database in Shaanxi

Zhongguo shuxue zazhi, 2023
Objective To analyze the commonality and characteristics between voluntary blood donors and hematopoietic stem cell donors in this region, and explore the potential for integration and development between China Marrow Donors Program (CMDP) and voluntary ...
Jun QI, Xiaoli CAO, Xin HU, Fengqin LI, Zhendong SUN, Yuhui LI, Manni WANG, Tianju WANG, Junhua WU, Lixia SHANG, Le CHEN, Hua XU   +11 more
doaj   +1 more source

Determination of an unrelated donor pool size for human leukocyte antigen-matched platelets in Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2016
Background: Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs
Carolina Bonet Bub, Margareth Afonso Torres, Maria Elisa Moraes, Nelson Hamerschlak, José Mauro Kutner   +4 more
doaj   +1 more source

Association of human platelet antigen polymorphisms with platelet count and mean platelet volume [PDF]

Hematology, 2018
Although recent genome-wide association studies have identified a number of single nucleotide polymorphisms associated with platelet count and mean platelet volume (MPV), it is unclear whether polymorphisms in the human platelet antigens (HPA) genes are associated with platelet count and MPV.
Shihang, Zhou, Xiaohua, Liang, Ni, Wang, Linnan, Shao, Weijian, Yu, Ming, Liu   +5 more
openaire   +2 more sources

Fatal Intracranial Haemorrhage due to HPA-2b Incompatible Foetal Alloimmune Thrombocytopenia and Antenatal Management of Subsequent Pregnancy

Journal of Clinical and Biomedical Sciences, 2016
Intracranial hemorrhage as a presenting feature of neonatal Alloimmune thrombocytopenia is an uncommon manifestation and is a predictor of recurrent risk in future pregnancy.
Arun Francis, Sarat Chandra G, Aruna Rajendran   +2 more
doaj   +1 more source

Neonatal alloimmune thrombocytopenia caused by anti-HPA antibodies in pregnant Chinese women: a study protocol for a multicentre, prospective cohort trial

BMC Pregnancy and Childbirth, 2017
Background Neonatal alloimmune thrombocytopenia (NAIT), caused by maternal antibodies raised against alloantigens carried on foetal platelets, is a very common haematological abnormality in newborns worldwide.
Li Chen, Zhiwei Liu, Tiemei Liu, Xianjun Ma, Meiying Rao, Yongjun Wang, Bo Sun, Wen Yin, Jun Zhang, Beizhan Yan, Xiaojuan Li, Qiushi Wang, Lei Zhang, Jun Wen, Fenghua Liu, Peng Wang, Yaming Wei, Yuanshuai Huang, Jiang Wu, Yi Guo, Yinlan Kang, Xiaochuan Song, Xiangfu Liu, Genling Zhang, Tingting Xie, Yonggeng Chen, Xiaojing Zeng, Zhongjun Li   +27 more
doaj   +1 more source