Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing [PDF]
Frontiers in Immunology, 2022 In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang +13 more
doaj +4 more sources
Gene frequency and distribution of human platelet antigen-1 to −6, −10, −15, and −21 of platelets donors in Wuhan, China [PDF]
Global Medical GeneticsBackground: In this study, the frequency of human platelet antigen (HPA) alleles and genotypes of platelet donors in Wuhan was evaluated and differences in HPA distribution between Wuhan and other regions in China were compared. Study Design and Methods:
Zhen Qu +6 more
doaj +4 more sources
THE IMPACT OF HUMAN PLATELET ANTIGEN ALLELE ON ANTIPLATELET ANTIBODIES AND CRYOGLOBULINS IN PATIENTS WITH PRIMARY IMMUNE THROMBOCYTOPENIA AND HEPATITIS C VIRUS-ASSOCIATED IMMUNE THROMBOCYTOPENIA [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2023 Background Human platelet antigens (HPAs) are alloantigens for antiplatelet alloantibodies and associated with the risk of immune thrombocytopenia (ITP). However, few studies have investigated associations among HPAs, antiplatelet autoantibodies, and
Cih-En Huang +9 more
doaj +2 more sources
Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors [PDF]
Einstein (São Paulo), 2019 Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra +6 more
doaj +4 more sources
Demand for human leukocyte antigen or human platelet antigen-selected platelets: An observational study at Canadian Blood Services. [PDF]
TransfusionAbstract Background Platelet transfusion refractoriness (PTR) is a clinically important condition. The Human Leukocyte Antigen and Human Platelet Antigen (HLA/HPA) Platelet Program at Canadian Blood Services (CBS) provides platelet products to support such patients.
Rickards N +5 more
europepmc +3 more sources
Human platelet antigen genotyping and expression of CD109 (human platelet antigen 15) mRNA in various human cell types. [PDF]
Biomed Res Int, 2013 CD109 gene encodes a glycosylphosphatidylinositol-linked glycoprotein found in a subset of platelets and endothelial cell, and human platelet antigen (HPA) 15 is found on CD109. We evaluated the HPA genotype and/or the CD109 mRNA expression on two peripheral blood stem cells (PBSC), two peripheral bloods (PB), 12 granulocyte products, natural killer ...
Hwang SM +8 more
europepmc +4 more sources
ABO Incompatibility between the Mother and Fetus Does Not Protect against Anti-Human Platelet Antigen-1a Immunization by Pregnancy [PDF]
Journal of Clinical Medicine, 2022 Ulrich Sachs +2 more
exaly +2 more sources
Clinical characteristics of human platelet antigen (HPA)‐1a and HPA‐5b alloimmunised pregnancies and the association between platelet HPA‐5b antibodies and symptomatic fetal neonatal alloimmune thrombocytopenia [PDF]
British Journal of Haematology, 2021 Dick Oepkes +2 more
exaly +2 more sources
Human platelet antigens – 2013 [PDF]
Vox Sanguinis, 2013 To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in alloimmune platelet disorders including foetal and neonatal alloimmune thrombocytopenia (FNAIT), posttransfusion purpura (PTP) and multitransfusion platelet refractoriness (MPR). The greatest
B R, Curtis, J G, McFarland
openaire +2 more sources
Zhongguo shuxue zazhi, 2022 Objective To evaluate the appropriate optimal capacity and matching probability of the platelet donor database with known HLA/HPA genotype in Shaanxi aera, and provide data support for subsequent construction, maintenance and application of the local ...
Jun QI +9 more
doaj +1 more source