Results 181 to 190 of about 365,728 (264)

Forward programming of human pluripotent stem cells to generate glutamatergic and GABAergic neurons in a tri-culture model with astrocytes. [PDF]

Stem Cell Res Ther
Gu J, Rollo B, Liu Z, O'Brien TJ, Kwan P, Cromer B, Sumer H.   +6 more
europepmc   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Dependence of cell fate potential and cadherin switching on the coordinate within the primitive streak during differentiation of human pluripotent stem cells. [PDF]

Development
Zhu Y, Warmflash A.
europepmc   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Robust generation of clinically applicable human pluripotent stem cells from peripheral blood by chemical reprogramming. [PDF]

Cell Discov
Fu X, Peng F, Cai R, Mao J, Liu T, Dong Y, Cheng R, Yang Z, Chen G, Li C, Mu R, Cheng L, Wang Y, Guan J, Deng H.   +14 more
europepmc   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Droplet microfluidics: Enabling the tailored fabrication of hydrogel particles

Droplet, EarlyView.
Droplet microfluidics enables precise, versatile fabrication of hydrogel particles with controlled size, composition, and structure. This review summarizes fundamental principles, engineering strategies, and emerging applications, providing a framework for advancing microfluidic hydrogel technologies.
Zhongqiao Gan, Xu Hou
wiley   +1 more source

Specific induction of right ventricular-like cardiomyocytes from human pluripotent stem cells. [PDF]

Stem Cell Res Ther
Saito Y, Nakamura K, Katanosaka Y, Iida T, Kusumoto D, Sato R, Adachi R, Shimizu S, Kurokawa J, Akagi S, Yoshida M, Miyoshi T, Morita H, Naruse K, Nishida M, Udono H, Zhang J, Yuasa S, Kamp TJ, Ito H.   +19 more
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Directed and efficient generation of calretinin interneurons from human pluripotent stem cells. [PDF]

Stem Cell Res Ther
Du X, Qi R, Li C, Zhou W, Wang S, Wei S, Wu R, Yin Y, Li T, Zhu X.   +9 more
europepmc   +1 more source