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Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Mark Rebeiz +9 more
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Characterization of human pluripotent stem cells
NeuroReport, 2013Human pluripotent stem cells (PSCs), whether embryonic stem cells or induced PSCs, offer enormous opportunities for regenerative medicine and other biomedical applications once we have developed the ability to harness their capacity for extensive differentiation. Central to this is our ability to identify and characterize such PSCs, but this is fraught
Paul J, Gokhale, Peter W, Andrews
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Bioenergetic Profiling of Human Pluripotent Stem Cells
2021Cellular metabolism contributes to cell fate decisions. Bioenergetic profiling can therefore provide considerable insights into cellular identity and specification. Given the current importance of human pluripotent stem cells (hPSCs) for biomedical applications, assessing the bioenergetic properties of hPSCs and derivatives can unveil relevant ...
Gizem, Inak +2 more
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Human Neural Crest Stem Cells Derived from Human Pluripotent Stem Cells
2014The neural crest cells give rise to neurons and glia in the peripheral nervous system, which is an important component of the nervous system. Here we developed a scalable process of inducing neural crest stem cells (NCSCs) from hESCs/iPSCs by a combination of growth factors in medium conditioned on stromal cells, and showed that NCSCs could be purified
Qiuyue, Liu +2 more
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Naiveté of the human pluripotent stem cell
Nature Biotechnology, 2014Human pluripotent stem cells can be stabilized in a state resembling the inner cell mass of the blastocyst.
Mascetti, Victoria L, Pedersen, Roger A
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Capacitation of Human Naïve Pluripotent Stem Cells
2021Naïve and primed pluripotent stem cells resemble epiblast cells of the pre-implantation and post-implantation embryo, respectively. This chapter describes a simple experimental system for the efficient and consistent transition of human pluripotent stem cells (hPSCs) from the naïve to the primed state, which is a process called capacitation.
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Generating melanocytes from human pluripotent stem cells
Pigment Cell & Melanoma Research, 2013Coverage on: Mica, Y., Lee, G., Chambers, S. M., Tomishima, M. J., and Studer, L. (2013). Modeling Neural Crest Induction, Melanocyte Specification, and Disease-Related Pigmentation Defects in hESCs and Patient-Specific iPSCS. Cell Reports 3, 1140-1152.
Varum Tavares, Sandra, Sommer, Lukas
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Human Pluripotent Stem Cell Differentiation to Microglia
2021Microglia, the immune cells of the central nervous system (CNS), play critical roles in CNS homeostasis and disease. Mounting evidence has linked aberrant microglial functions to neurodevelopment, neuroinflammatory and neurodegenerative diseases, underlining the need for novel models to investigate human microglia biology.
Laraib, Ijaz +2 more
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[Human pluripotent stems cells I].
Revista de medicina de la Universidad de Navarra, 2004In the last few years, the great progress of certain fields, such as molecular biology and development, has allowed a detailed knowledge of mechanisms implicated in cellular programing. This has permitted a rapid and unexpected advance in therapeutic cellular strategies.
N, López Moratalla +1 more
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