Results 251 to 260 of about 216,145 (304)

Differentiation of human pluripotent stem cells into urothelial organoids via transient activation of WNT signaling. [PDF]

iScience
Qu N, Daoud A, Kechele DO, Cleary CE, Múnera JO.   +4 more
europepmc   +1 more source

Elevation of Stearoyl‐Coenzyme A Desaturase and Monounsaturated Fatty Acids in Parkinson's Disease Serum

Movement Disorders, EarlyView.
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik, Russell Pickford, Michelle Chua, Simon J.G. Lewis, Nicolas Dzamko, Woojin Scott Kim   +5 more
wiley   +1 more source

Gain of 20q11.21 in human pluripotent stem cells enhances differentiation to retinal pigment epithelium. [PDF]

Stem Cell Res Ther
Vitillo L, Anjum F, Hewitt Z, Laing O, Ababneh NA, Baker D, Barbaric I, Coffey PJ.   +7 more
europepmc   +1 more source

Biomarkers of Leucine‐Rich Repeat Kinase 2 (LRRK2) and Lysosomal Dysfunction in Progressive Supranuclear Palsy

Movement Disorders, EarlyView.
Abstract Background Common and rare genetic variants in leucine‐rich repeat kinase 2 (LRRK2) have been linked with sporadic and familial Parkinson's disease (PD). Recently, we discovered that common genetic variation near the LRRK2 locus determined survival in progressive supranuclear palsy (PSP).
Louise‐Kristine Nielsen, Joshua L.I. Frost, David P. Vaughan, Raquel Real, Riona Fumi, Marte Theilmann Jensen, Megan Hodgson, Eleanor J. Stafford, Lesley Wu, Olaf Ansorge, Annelies Quaegebeur, Kieren S.J. Allinson, Thomas T. Warner, Zane Jaunmuktane, Anjum Misbahuddin, P. Nigel Leigh, Boyd C.P. Ghosh, Kailash P. Bhatia, Alistair Church, Christopher Kobylecki, Michele T.M. Hu, James B. Rowe, Alan A. Shomo, Danielle L. Graham, Omar S. Mabrouk, Huw R. Morris, Esther M. Sammler, Edwin Jabbari   +27 more
wiley   +1 more source

Temporal Regulation of Cytokines and Growth Factors for Optimized Hematopoietic-Lineage Specification from Human Pluripotent Stem Cells. [PDF]

Int J Stem Cells
Park J, Koh H, Jeon E, Uh K, Kim S, Lee JH.   +5 more
europepmc   +1 more source

Differentiation of Cardiomyocytes from Human Pluripotent Stem Cells Using Monolayer Culture

Biomarker Insights, 2015
Ivan Batalov, Adam W. Feinberg
doaj  

Protocol for differentiation of human pluripotent stem cells into definitive endoderm lineage in a chemically defined and growth factor-free system. [PDF]

STAR Protoc
En H, Guo Y, Zhao Z, Huang X, Cao N, Wang J.   +5 more
europepmc   +1 more source

Heparan sulfate regulates the fate decisions of human pluripotent stem cells. [PDF]

Stem Cell Reports
Syangtan D, Al Mahbuba D, Masuko S, Li Q, Elton AC, Zaltsman Y, Wrighton PJ, Xia K, Han X, Ouyang Y, Zhang F, Linhardt RJ, Kiessling LL.   +12 more
europepmc   +1 more source

Modeling of skeletal development and diseases using human pluripotent stem cells. [PDF]

J Bone Miner Res
Hojo H, Tani S, Ohba S.
europepmc   +1 more source

Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors. [PDF]

Cell Stem Cell
Doulatov S, Vo LT, Chou SS, Kim PG, Arora N, Li H, Hadland BK, Bernstein ID, Collins JJ, Zon LI, Daley GQ.   +10 more
europepmc   +1 more source