Results 131 to 140 of about 18,748 (164)

Human demyelinating disease and the polyomavirus JCV

Multiple Sclerosis Journal, 2006
Many human neurological diseases involve demyelination of the central and/or peripheral nervous systems. These include the hereditary leukodystrophies -which have a genetic basis; multiple sclerosis (MS) -where the underlying cause of demyelination remains unknown; and progressive multifocal leukoencephalopathy (PML) -where the etiology is well ...
K, Khalili, M K, White
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Detection of Human Polyomavirus 7 in Human Thymic Epithelial Tumors [PDF]

Journal of Thoracic Oncology, 2015
Although the molecular genetics possibly underlying the pathogenesis of human thymoma have been extensively studied, its etiology remains poorly understood. Because murine polyomavirus consistently induces thymomas in mice, we assessed the presence of the novel human polyomavirus 7 (HPyV7) in human thymic epithelial tumors.HPyV7-DNA Fluorescence in ...
Ernst-Jan Speel, Axel Zur Hausen, Christopher Buck   +2 more
exaly   +4 more sources

Polyomavirus in Human Cancer Development

2007
In animal studies, polyoma viruses have been found to be viral agents for oncogenesis and to produce a wide range of pathological lesions in experimental animals, including a variety of neoplastic tumors. The human polyoma viruses (JCV and BKV), along with their simian cousin (SV40), are ubiquitous viruses that are primarily associated with progressive
Winston, Lee, Erik, Langhoff
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Transplacental transmission of human polyomavirus BK

Journal of Medical Virology, 1998
The presence of BK virus (BKV) and JC virus (JCV) in autopsy materials (placenta, brain, and kidney) of aborted fetuses was investigated by PCR using two sets of primers, specific for the regulatory region (RR) and for the capsid protein VP1, respectively.
PIETROPAOLO, Valeria Antonietta, DI TARANTO C., DEGENER, Anna Marta, JIN L., SINIBALDI, Laura, BAIOCCHINI A., MELIS, Marco, ORSI, Nicola   +7 more
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Human exposure to bovine polyomavirus: A zoonosis?

Archives of Virology, 1986
A competitive-type solid phase radioimmunoassay (RIA) was developed for the detection of antibody to bovine polyomavirus. Comparison of RIA and counter-immunoelectrophoresis (CIE) results on 273 cattle sera indicated that both techniques were detecting antibody of like specificity.
J V, Parry, S D, Gardner
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Update on human polyomavirus BK nephropathy

Diagnostic Cytopathology, 2009
AbstractPolyomavirus BK (BKV) has ebeen identified as the main cause of polyomavirus‐associated nephropathy, a major cause of renal allograft failure. Although BKV‐associated nephropathy develops in only 2% to 5% of renal transplant recipients, its prognosis when present is very poor, with irreversible graft failure developing in 45% of affected ...
David, Cimbaluk, Lisa, Pitelka, Larry, Kluskens, Paolo, Gattuso   +3 more
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Interaction of the human polyomavirus, JCV, with human B-lymphocytes

Virology, 1992
The human polyomavirus, JCV, is the causative agent of the central nervous system demyelinating disease progressive multifocal leukoencephalopathy (PML). The principal target of JCV infection in the central nervous system (CNS) is the myelinating oligodendrocyte.
W J, Atwood, K, Amemiya, R, Traub, J, Harms, E O, Major   +4 more
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Mixed infection with human cytomegalovirus and human polyomavirus (BKV)

Journal of Medical Virology, 1984
AbstractMixed infection, the infection of a single cell by two distinguishable viruses, has been demonstrated electron microscopically in human embryo lung (HEL) and human embryo kidney (HEK) cells infected with human cytomegalovirus (HCMV) and human polyomavirus (BKV). There was no evidence of enhancement of HCMV by BKV in either cell system; however,
S C, Goldstein, T S, Tralka, A S, Rabson
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Oncogenic potentials of the human polyomavirus regulatory proteins

Cellular and Molecular Life Sciences, 2007
The polyomaviruses BK, JC and SV40 are common in the human population. Their DNA genomes encode large T-antigen, small t-antigen, agnoprotein, and the capsid proteins VP1-3. Studies with these viruses have contributed extensively to the understanding of processes such as replication, transcriptional and posttranscriptional regulation, and cell cycle ...
U, Moens, M, Van Ghelue, M, Johannessen
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A Prospective Study of Human Polyomavirus Infection in Pregnancy

Obstetrical & Gynecological Survey, 1980
Urine samples from 1,235 pregnant women were examined by light microscopy for cytologic evidence of virus infection. Smears of urine sediment from 40 women (3.2%) were observed to contain inclusion-bearing cells; polyomavirus infection was confirmed by virologic methods in 24 (60%). A polyomavirus was isolated from 12 women.
D V, Coleman, M R, Wolfendale, R A, Daniel, N K, Dhanjal, S D, Gardner, P E, Gibson, A M, Field   +6 more
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